Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28643916 | 1.00 | CYP2D6 (0.41) | CYP2D6HRH3TSHRHIF1AKCNH2 | |
| SCHEMBL1456783 | 1.00 | CYP2D6 (0.41) | CYP2D6HRH3TSHRHIF1AKCNH2 | |
| Hydrochloric Acid SCHEMBL4633661 | 0.98 | CYP2D6 (0.40) | CYP2D6HRH3TSHRHIF1AKCNH2 | |
| SCHEMBL1827943 | 0.98 | LTA4H (0.40) | CYP2D6HRH3TSHRHIF1AKCNH2 | |
| SCHEMBL1829382 | 0.93 | LTA4H (0.39) | CYP2D6HRH3TSHRHIF1ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5223635 | 0.91 | LTA4H (0.38) | CYP2D6HRH3TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL188044 | 0.87 | ALDH1A1 (0.41) | CYP2D6HRH3KCNH2CYP2C19SMN1; SMN2 | |
| SCHEMBL7171239 | 0.87 | LTA4H (0.43) | TSHRLTA4HKDM4EMEN1KMT2A | |
| SCHEMBL1802067 | 0.82 | LTA4H (0.58) | HRH3LTA4H | |
| SCHEMBL7723416 | 0.77 | ALDH1A1 (0.35) | CYP2D6HRH3CYP2C19SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107441765-B | Extraction composition, extraction system and application thereof | 中国科学院上海有机化学研究所 | 2021-04-20 | — | — | CN | claimed |
| EP-1898909-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2016-10-19 | — | — | EP | claimed |
| EP-2841426-B1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2016-09-28 | — | — | EP | claimed |
| EP-1898910-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2016-09-28 | — | — | EP | claimed |
| EP-2697232-B1 | 6,7-DIHYDROIMIDAZO[2,1-B][1,3]OXAZINE BACTERICIDES | OTSUKA PHARMA CO LTD (JP) | 2016-05-18 | — | — | EP | claimed |
| EP-2841425-B1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2016-03-23 | — | — | EP | claimed |
| EP-2099758-B1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2016-03-09 | — | — | EP | claimed |
| EP-1912948-B1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2015-09-09 | — | — | EP | claimed |
| US-9051333-B2 | 6,7-dihydroimidazo [2,1-b] [1,3]oxazine bactericides | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-06-09 | — | — | US | claimed |
| EP-2697232-A1 | 6,7 - DIHYDROIMIDAZO [2, 1 - B][1, 3]OXAZINE BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-02-19 | — | — | EP | claimed |
| EP-1753427-B1 | USE OF SUBSTITUTED QUINOLINE DERIVATIVES FOR THE TREATMENT OF DRUG RESISTANT MYCOBACTERIAL DISEASES | JANSSEN PHARMACEUTICA NV (BE) | 2008-04-02 | — | — | EP | claimed |
| CN-101080402-A | Hydantoin derivatives useful as metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2007-11-28 | — | — | CN | claimed |
| EP-1828166-A1 | HYDANTOIN DERIVATIVES USEFUL AS METALLOPROTEINASE INHIBITORS | AstraZeneca AB (SE) | 2007-09-05 | — | — | EP | claimed |
| WO-2006064218-A1 | HYDANTOIN DERIVATIVES USEFUL AS METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | claimed |
| WO-2006044762-A2 | TETRAHYDRO-5H-PYRIMIDO[4,5-D]AZEPINE DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES ASSOCIATED WITH THE 5-HT2C RECEPTOR | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-04-27 | — | — | WO | claimed |
| US-20050131021-A1 | Phenoxy piperidines for treating diseases such as schizophrenia and depression | MERCK PATENT GMBH (DE) | 2005-06-16 | — | — | US | claimed |
| JP-2005514457-A | — | — | 2005-05-19 | — | — | JP | claimed |
| EP-1465868-A1 | PHENOXY PIPERIDINES FOR TREATING DISEASES SUCH AS SCHIZOPHRENIA AND DEPRESSION | MERCK PATENT GmbH (DE) | 2004-10-13 | — | — | EP | claimed |
| WO-2003059882-A1 | PHENOXY PIPERIDINES FOR TREATING DISEASES SUCH AS SCHIZOPHRENIA AND DEPRESSION | MERCK PATENT GMBH (DE) | 2003-07-24 | — | — | WO | claimed |
| EP-0023706-B1 | 4-PHENOXY PIPERIDINES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-03-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131021-A1 | Phenoxy piperidines for treating diseases such as schizophrenia and depression | CHRM1, CHRNA3, CHRM2 | CYP2D6 3294/4885HRH3 123/4885TSHR 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.