Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18872129 | 0.76 | ATM (0.56) | MAPTMEN1KMT2AHPGDTDP1 | |
| SCHEMBL18804144 | 0.72 | L3MBTL1 (0.47) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL18859795 | 0.71 | HPRT1 (0.47) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL18805451 | 0.70 | MAPT (0.41) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL9506713 | 0.66 | MAPT (0.50) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL11767284 | 0.64 | MAPT (0.46) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL28932849 | 0.63 | S100A4 (0.52) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL28769752 | 0.63 | HPGD (0.50) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL28556282 | 0.60 | MCL1 (0.56) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL2975952 | 0.59 | ROCK1 (0.43) | LMNAMAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162806-A2 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | Heesung Material Ltd. (KR) | 2017-05-03 | — | — | EP | disclosed |