Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28932849 | 0.78 | S100A4 (0.52) | MAPTKMT2AHPGDMEN1LMNA | |
| SCHEMBL28769752 | 0.78 | HPGD (0.50) | MAPTKMT2AHPGDMEN1TSHR | |
| SCHEMBL18859795 | 0.77 | HPRT1 (0.47) | MAPTKMT2AHPGDMEN1TSHR | |
| SCHEMBL963270 | 0.76 | HASPIN (0.40) | MAPTKMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL18804144 | 0.75 | L3MBTL1 (0.47) | MAPTKMT2AHPGDMEN1TSHR | |
| SCHEMBL11767284 | 0.75 | MAPT (0.46) | MAPTKMT2AHPGDMEN1TSHR | |
| SCHEMBL28556282 | 0.74 | MCL1 (0.56) | MAPTKMT2AHPGDMEN1LMNA | |
| SCHEMBL2164909 | 0.73 | MAPT (0.43) | MAPTKMT2AHPGDMEN1TSHR | |
| SCHEMBL2165461 | 0.73 | LMNA (0.43) | MAPTKMT2AHPGDMEN1TSHR | |
| SCHEMBL2164911 | 0.73 | MAPT (0.43) | MAPTKMT2AHPGDMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5001056-A | — | — | None | — | — | JP | disclosed |
| CN-116606186-A | Aromatic nitro compound and preparation method thereof | 川北医学院 | 2023-08-18 | — | — | CN | disclosed |
| JP-H051056-A | BENZOTHIOPHENE COMPOUND | SEIKO EPSON CORP | 1993-01-08 | — | — | JP | disclosed |