Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16923658 | 0.85 | PAOX (0.42) | PAOXKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16923659 | 0.85 | CYP2D6 (0.43) | PAOXKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL15374964 | 0.85 | PAOX (0.42) | PAOXKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL22360772 | 0.83 | PAOX (0.40) | PAOXKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL15495130 | 0.78 | ALDH1A1 (0.50) | PAOXKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL24864612 | 0.77 | PAOX (0.52) | PAOXKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12226462 | 0.77 | HSD11B1 (0.47) | PAOXKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL26511075 | 0.74 | PAOX (0.44) | PAOXKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8060957 | 0.73 | NPSR1 (0.46) | PAOXKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL13527664 | 0.73 | NPSR1 (0.46) | PAOXKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2846838-B1 | POLYMER CONJUGATES WITH A LINKER | NITTO DENKO CORP (JP) | 2017-05-03 | — | — | EP | disclosed |