Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16935687 | 0.87 | MDM4 (0.36) | MDM4TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL7654908 | 0.86 | MDM4 (0.35) | MDM4TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL7649860 | 0.86 | MDM4 (0.35) | MDM4TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL28037278 | 0.86 | TAAR1 (0.50) | — | |
| SCHEMBL8127204 | 0.86 | TAAR1 (0.50) | — | |
| SCHEMBL7654892 | 0.86 | MDM4 (0.35) | MDM4TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL7648446 | 0.86 | L3MBTL1 (0.46) | MDM4TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL8127206 | 0.86 | TAAR1 (0.50) | — | |
| SCHEMBL28037694 | 0.83 | TAAR1 (0.37) | MDM4TP53MEN1KMT2AALDH1A1 | |
| SCHEMBL3769268 | 0.82 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130303491-A1 | Antiviral Drugs for Treatement or Prevention of Dengue Infection | SIGA TECHNOLOGIES INC. (US) | 2013-11-14 | — | — | US | claimed |
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | SIGA TECHNOLOGIES, INC. | 2010-07-29 | — | — | US | claimed |
| EP-2148678-A1 | ANTIVIRAL DRUGS FOR TREATMENT OR PREVENTION OF DENGUE INFECTION | Siga Technologies, Inc. (US) | 2010-02-03 | — | — | EP | claimed |
| WO-2008147962-A1 | ANTIVIRAL DRUGS FOR TREATMENT OR PREVENTION OF DENGUE INFECTION | SIGA TECHNOLOGIES, INC. (US) | 2008-12-04 | — | — | WO | claimed |
| US-5807869-A | Quinoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-15 | — | — | US | claimed |
| US-20160250233-A1 | ANTIVIRAL DRUGS FOR TREATMENT OR PREVENTION OF DENGUE INFECTION | SIGA TECHNOLOGIES, INC. (US) | 2016-09-01 | — | — | US | disclosed |
| US-9353051-B2 | Antiviral drugs for treatment or prevention of dengue infection | SIGA TECHNOLOGIES, INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-20130303491-A1 | Antiviral Drugs for Treatement or Prevention of Dengue Infection | SIGA TECHNOLOGIES INC. (US) | 2013-11-14 | — | — | US | disclosed |
| US-8518960-B2 | Antiviral drugs for treatment or prevention of dengue infection | SIGA TECHNOLOGIES, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| US-8350995-B2 | Optical film, production method of optical film, optically-compensatory film, polarizing plate and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2013-01-08 | — | — | US | disclosed |
| CN-101322055-B | Retardation film, method for producing retardation film, polarizing plate, and liquid crystal display device | KONICA MINOLTA OPTO INC | 2012-08-29 | — | — | CN | disclosed |
| CN-101300307-B | Polymer film, method for producing polymer film, optical film and polarizing plate, and liquid crystal display device using the polarizing plate | FUJI PHOTO FILM CO LTD | 2012-05-09 | — | — | CN | disclosed |
| EP-0906115-A1 | COMBINED USE OF GnRH AGONIST AND ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0876349-A1 | QUINOLINE DERIVATIVES AS GNRH ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5807869-A | Quinoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| WO-1997040846-A1 | COMBINED USE OF GnRH AGONIST AND ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-11-06 | — | — | WO | disclosed |
| EP-0781774-A2 | Prolactin production inhibitory agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |
| WO-1997014682-A1 | QUINOLINE DERIVATIVES AS GNRH ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |
| US-4392999-A | COLORFAST BROWN, RED AND ORANGE | CIBA-GEIGY CORPORATION (US) | 1983-07-12 | — | — | US | disclosed |
| US-4229344-A | Monazo pigments containing hydroxynaphthoylaminobenzimidazalone radical | CIBA-GEIGY CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303491-A1 | Antiviral Drugs for Treatement or Prevention of Dengue Infection | HAVCR2, EIF2AK2, ZC3HAV1 | MDM4 3926/4885TP53 3871/4885MEN1 2863/4885 |
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | EIF2AK2, HAVCR2, SNRPE | MDM4 4032/4885TP53 3919/4885MEN1 3401/4885 |
| US-20160250233-A1 | ANTIVIRAL DRUGS FOR TREATMENT OR PREVENTION OF DENGUE INFECTION | EIF2AK2, HAVCR2, SNRPE | MDM4 4032/4885TP53 3919/4885MEN1 3401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.