Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | CIT | O14578 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127206 | 0.87 | TAAR1 (0.50) | TAAR1IDO1XIAPBIRC2CTRB1 | |
| SCHEMBL28037278 | 0.87 | TAAR1 (0.50) | TAAR1IDO1XIAPBIRC2CTRB1 | |
| SCHEMBL8127204 | 0.87 | TAAR1 (0.50) | TAAR1IDO1XIAPBIRC2CTRB1 | |
| SCHEMBL16935687 | 0.85 | MDM4 (0.36) | TAAR1GLSMDM4TP53MEN1 | |
| SCHEMBL1880904 | 0.83 | MDM4 (0.49) | MDM4TP53MEN1ALDH1A1MAPT | |
| SCHEMBL7648446 | 0.80 | L3MBTL1 (0.46) | MDM4TP53MEN1ALDH1A1MAPT | |
| SCHEMBL7654892 | 0.80 | MDM4 (0.35) | TAAR1MDM4TP53XIAPBIRC2 | |
| SCHEMBL7654908 | 0.80 | MDM4 (0.35) | TAAR1MDM4TP53MEN1ALDH1A1 | |
| SCHEMBL7649860 | 0.80 | MDM4 (0.35) | TAAR1MDM4TP53MEN1ALDH1A1 | |
| SCHEMBL16935722 | 0.76 | CTRC (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164124-A | Compounds and compositions for treating parasitic diseases | NOVARTIS AG | 2015-12-16 | — | — | CN | disclosed |