Dipyridyl

Dipyridyl

SCHEMBL1881386

Nc1ccnc(-c2ccccn2)c1N.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.54
LMNA P02545 3/20 0.54
CCR1 P32246 3/20 0.54
CCR5 P51681 3/20 0.54
CCR8 P51685 3/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
METAP1 P53582 1/20 0.54
BLM P54132 1/20 0.54
HIF1A Q16665 1/20 0.54
DOHH Q9BU89 1/20 0.54
P4HTM Q9NXG6 1/20 0.54
ULK1 O75385 1/20 0.49
CDK7 P50613 1/20 0.49
CDK5 Q00535 1/20 0.49
PRKCE Q02156 1/20 0.49
CAMK2G Q13555 1/20 0.49
DYRK1A Q13627 1/20 0.49
CDK5R1 Q15078 1/20 0.49
RPS6KA1 Q15418 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL8034233 0.98 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL517415 0.98 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30671645 0.96 ULK1 (0.49) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7875060 0.96 ULK1 (0.49) KDM4ELMNACCR1CCR5CCR8
SCHEMBL1513867 0.82 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL31634390 0.82 TDO2 (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28593136 0.78 ULK1 (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30791149 0.78 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL310349 0.78 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL28562697 0.77 KDM4E (0.74) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2764362-B1 DYE CONJUGATED PEPTIDES FOR FLUORESCENT IMAGING IMMUNOMEDICS INC (US) 2018-09-05 EP claimed
US-6319668-B1 TARGET MOLECULES WITH LINKING TO MATRIX, IMPRINTING AN OPTICAL READ SYMBOL, PROGRAMMING A REMOTE MEMORY AND REPEATING UNTIL SYNTHESIS IS COMPLETE DISCOVERY PARTNERS INTERNATIONAL 2001-11-20 US claimed
EP-0853497-A2 MATRICES WITH MEMORIES, SENSORS WITH MEMORIES AND USES THEREOF Irori (US) 1998-07-22 EP claimed
WO-1997012680-A9 MATRICES WITH MEMORIES, SENSORS WITH MEMORIES AND USES THEREOF 1998-02-26 WO claimed
EP-0822861-A1 REMOTELY PROGRAMMABLE MATRICES WITH MEMORIES AND USES THEREOF Irori (US) 1998-02-11 EP claimed
WO-1997012680-A2 MATRICES WITH MEMORIES, SENSORS WITH MEMORIES AND USES THEREOF IRORI (US) 1997-04-10 WO claimed
WO-1996036436-A1 REMOTELY PROGRAMMABLE MATRICES WITH MEMORIES AND USES THEREOF IRORI (US) 1996-11-21 WO claimed
CN-109963872-B Diagnostic anti-PD-L1 antibodies and uses thereof 默克专利股份有限公司 2023-04-11 CN disclosed
EP-3729088-B1 DIAGNOSIS AND TREATMENT OF ALPHA-SYNUCLEINOPATHIES H LUNDBECK AS (DK) 2021-10-20 EP disclosed
EP-3729088-A1 ASSAY, METHOD AND TREATMENT OF ALPHA-SYNUCLEINOPATHIES H. Lundbeck A/S (DK) 2020-10-28 EP disclosed
US-20200309796-A1 ASSAY, METHOD AND TREATMENT OF ALPHA-SYNUCLEINOPATHIES H. LUNDBECK A/S (DK) 2020-10-01 US disclosed
EP-3091978-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING IMIQUIMOD FOR USE IN THE TREATMENT OF CARCINOMA IN SITU OF THE BLADDER Urogen Pharma Ltd. (IL) 2016-11-16 EP disclosed
WO-2015104219-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING IMIQUIMOD FOR USE IN THE TREATMENT OF CARCINOMA IN SITU OF THE BLADDER TELORMEDIX SA (CH) 2015-07-16 WO disclosed
EP-0569496-B1 METHOD OF MEASURING LUMINESCENCE IN AN ASSAY BY LUMINESCENCE CIS BIO INT (FR) 1994-09-21 EP disclosed
EP-0569496-A1 METHOD OF MEASURING LUMINESCENCE IN AN ASSAY BY LUMINESCENCE. CIS BIO INT (FR) 1993-11-18 EP disclosed
EP-0539435-A1 METHOD FOR REDUCING INTERFERENCE IN A FLUORESCENT ASSAY. CIS BIO INT (FR) 1993-05-05 EP disclosed
EP-0539477-A1 METHOD FOR AMPLIFYING A SIGNAL EMITTED BY A LUMINESCENT COMPOUND. CIS BIO INT (FR) 1993-05-05 EP disclosed
WO-1992013264-A1 METHOD OF MEASURING LUMINESCENCE IN AN ASSAY BY LUMINESCENCE CIS BIO INTERNATIONAL (FR) 1992-08-06 WO disclosed
WO-1992001224-A1 METHOD FOR REDUCING INTERFERENCE IN A FLUORESCENT ASSAY CIS BIO INTERNATIONAL (FR) 1992-01-23 WO disclosed
WO-1992001225-A1 METHOD FOR AMPLIFYING A SIGNAL EMITTED BY A LUMINESCENT COMPOUND CIS BIO INTERNATIONAL (FR) 1992-01-23 WO disclosed