Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 3/20 | 0.52 |
| ▸ | CCR8 | P51685 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | METAP1 | P53582 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | ULK1 | O75385 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL1881386 | 0.98 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL7875060 | 0.98 | ULK1 (0.49) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL517415 | 0.96 | KDM4E (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL30671645 | 0.94 | ULK1 (0.49) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL1513867 | 0.81 | KDM4E (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL31634390 | 0.81 | TDO2 (0.42) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL28593136 | 0.76 | ULK1 (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL30791149 | 0.76 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL310349 | 0.76 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL28562697 | 0.75 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983388-A1 | METHOD FOR DETECTING QUALITATIVE AND QUANTITATIVE ALTERATIONS IN DNA AND LIGANDS OF SAID ALTERATION LIGANDS | Genolife (FR) | 2000-03-08 | — | — | EP | disclosed |
| US-6020212-A | Phycobiliprotein-linker peptide complex fluorescent tracer and methods of using the same | CIS BIO INTERNATIONAL (FR) | 2000-02-01 | — | — | US | disclosed |
| WO-1998053099-A1 | METHOD FOR DETECTING QUALITATIVE AND QUANTITATIVE ALTERATIONS IN DNA AND LIGANDS OF SAID ALTERATION LIGANDS | GENOLIFE (FR) | 1998-11-26 | — | — | WO | disclosed |