SCHEMBL188149

SCHEMBL188149

O=C(O)C1=C(c2ccccc2)C(=O)NC1=O

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.53
FGFR1 P11362 2/20 0.52
FGFR2 P21802 2/20 0.52
FGFR4 P22455 2/20 0.52
FGFR3 P22607 2/20 0.52
GSK3B P49841 10/20 0.50
SRC P12931 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28232183 0.85 FGFR1 (0.54) PTGS2FGFR1FGFR2FGFR4FGFR3
SCHEMBL18498965 0.83 ALDH1A1 (0.56) PTGS2FGFR1FGFR2FGFR4FGFR3
SCHEMBL114611 0.80 PTGS2 (0.67) PTGS2GSK3B
SCHEMBL10929771 0.79 PTGS2 (0.49) PTGS2GSK3BHSP90AA1HSP90AB1
SCHEMBL15129226 0.79 PTGS2 (0.45) PTGS2FGFR1FGFR2FGFR4FGFR3
SCHEMBL14065347 0.78 FGFR1 (0.46) PTGS2FGFR1FGFR2FGFR4FGFR3
SCHEMBL9474080 0.78 PTGS2 (0.64) PTGS2GSK3B
SCHEMBL187764 0.75 PTGS2 (0.61) PTGS2GSK3B
SCHEMBL8656807 0.74 FGFR1 (0.70) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL29273155 0.74 FGFR1 (0.70) FGFR1FGFR2FGFR4FGFR3SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110198927-A Process for purifying N-substituted maleimides 株式会社LG化学 2019-09-03 CN claimed
CN-108055849-A Method for preparing vinyl chloride copolymer and vinyl chloride copolymer prepared by the same 株式会社LG化学 2018-05-18 CN claimed
EP-1795645-B1 COATING LIQUID FOR COVERING GLASS FIBER AND RUBBER-REINFORCING GLASS FIBER USING SAME CENTRAL GLASS CO LTD (JP) 2018-04-18 EP claimed
US-8455097-B2 Coating liquid for covering glass fiber and rubber-reinforcing glass fiber using same CENTRAL GLASS COMPANY, LIMITED (JP) 2013-06-04 US claimed
CN-1532566-B Radiation sensitive composition for color filter JSR CORP 2010-05-12 CN claimed
EP-2160422-A1 MALEIMIDE-ALPHA-ALKYLSTYRENE-BASED TERPOLYMER WITH LOW MOLTEN VISCOSITY AND CONTINUOUS BULK PROCESS FOR PRODUCING IT Korea Kumho Petrochemical Co., Ltd. (KR) 2010-03-10 EP claimed
EP-2066708-A1 MALEIMIDE-ALPHA-ALKYLSTYRENE-BASED TETRAPOLYMER WITH LOW MOLTEN VISCOSITY AND CONTINUOUS BULK PROCESS FOR PRODUCING IT Korea Kumho Petrochemical Co., Ltd. (KR) 2009-06-10 EP claimed
WO-2008153243-A1 MALEIMIDE-ALPHA-ALKYLSTYRENE-BASED TERPOLYMER WITH LOW MOLTEN VISCOSITY AND CONTINUOUS BULK PROCESS FOR PRODUCING IT KOREA KUMHO PETROCHEMICAL CO., LTD (KR) 2008-12-18 WO claimed
US-20080280715-A1 Coating Liquid for Covering Glass Fiber and Rubber-Reinforcing Glass Fiber Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2008-11-13 US claimed
WO-2008038857-A1 MALEIMIDE-ALPHA-ALKYLSTYRENE-BASED TETRAPOLYMER WITH LOW MOLTEN VISCOSITY AND CONTINUOUS BULK PROCESS FOR PRODUCING IT KOREA KUMHO PETROCHEMICAL CO., LTD (KR) 2008-04-03 WO claimed
EP-1795645-A1 COATING LIQUID FOR COVERING GLASS FIBER AND RUBBER-REINFORCING GLASS FIBER USING SAME Central Glass Company, Limited (JP) 2007-06-13 EP claimed
US-12534584-B2 Resin composition, prepreg, resin-attached film, resin-attached metal foil, metal-cladded laminate sheet, and wiring board PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2026-01-27 US disclosed
CN-119013284-A Alkylsilyl peroxide, thermosetting composition, resin film, prepreg, metal laminate and printed wiring board 日油株式会社 2024-11-22 CN disclosed
WO-2024101362-A1 RESIN COMPOSITION, PREPREG, METAL-CLAD LAMINATE, WIRING BOARD, METAL FOIL WITH RESIN, AND FILM WITH RESIN パナソニックIPマネジメント株式会社 2024-05-16 WO disclosed
WO-2024070840-A1 ALKYL SILYL PEROXIDE, HEAT-CURABLE COMPOSITION, RESIN FILM, PREPREG, METAL LAMINATE, AND PRINTED WIRING BOARD 日油株式会社 2024-04-04 WO disclosed
EP-1795645-A1 COATING LIQUID FOR COVERING GLASS FIBER AND RUBBER-REINFORCING GLASS FIBER USING SAME Central Glass Company, Limited (JP) 2007-06-13 EP disclosed
US-7175969-B1 Method of preparing negative-working radiation-sensitive elements EASTMAN KODAK COMPANY (US) 2007-02-13 US disclosed
CN-1532566-A Radiation sensitive composition for color filter JSR株式会社 2004-09-29 CN disclosed
JP-2001019744-A CURING AGENT USED FOR EPOXY RESIN IND TECHNOL RES INST 2001-01-23 JP disclosed
US-5428057-A Curing agent; curing catalyst; stress lowering agent; heat resistance-improving agent CHEIL INDUSTRIES, INC. (KR) 1995-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534584-B2 Resin composition, prepreg, resin-attached film, resin-attached metal foil, metal-cladded laminate sheet, and wiring board MECP2, WDR33, TERB1 PTGS2 1554/4885FGFR1 2356/4885FGFR2 1706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.