SCHEMBL28232183

SCHEMBL28232183

NC(=O)C1=C(c2ccccc2)C(=O)NC1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 3/20 0.54
FGFR2 P21802 3/20 0.54
FGFR4 P22455 3/20 0.54
FGFR3 P22607 3/20 0.54
SRC P12931 2/20 0.54
CRHBP P24387 1/20 0.54
CRHR2 Q13324 1/20 0.54
PTGS2 P35354 5/20 0.50
GSK3B P49841 9/20 0.47
BCAT2 O15382 1/20 0.40
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
PARP1 P09874 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL188149 0.85 PTGS2 (0.53) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL18498965 0.80 ALDH1A1 (0.56) FGFR1FGFR2FGFR4FGFR3PTGS2
SCHEMBL114611 0.77 PTGS2 (0.67) PTGS2GSK3B
SCHEMBL10929771 0.76 PTGS2 (0.49) PTGS2GSK3B
SCHEMBL15129226 0.76 PTGS2 (0.45) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL9474080 0.75 PTGS2 (0.64) PTGS2GSK3B
SCHEMBL3164032 0.72 PTGS2 (0.55) PTGS2GSK3B
SCHEMBL187764 0.72 PTGS2 (0.61) PTGS2GSK3B
SCHEMBL144665 0.70 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3SRC
SCHEMBL13579027 0.70 MKNK1 (0.49) PTGS2GSK3BPOLBCYP3A4PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108314850-A Rubber composition and processing method, and apply its rubber product and production method 杭州星庐科技有限公司 2018-07-24 CN claimed