SCHEMBL188152

SCHEMBL188152

C=Cc1ccc(COC(C)N(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
IDO1 P14902 2/20 0.31
HDAC8 Q9BY41 1/20 0.31
TSHR P16473 1/20 0.30
RCE1 Q9Y256 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5199701 0.82 ALDH1A1 (0.44) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL21156384 0.79 ALDH1A1 (0.41) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL9324006 0.77 ALDH1A1 (0.48) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL5069327 0.77 ALDH1A1 (0.39) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL3957537 0.77 ALDH1A1 (0.39) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL6310633 0.77 ALDH1A1 (0.39) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL1081809 0.77 ALDH1A1 (0.39) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL4440288 0.77 ALDH1A1 (0.39) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL15624242 0.76 ALDH1A1 (0.38) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL10782592 0.76 TSHR (0.44) ALDH1A1IDO1TSHRRCE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115836106-B Materials with structured surfaces capable of being painted and painted 弗瑞兹艾格有限及两合公司 2024-08-02 CN claimed
CN-115836106-A Lacquerable and lacquered material with a structured surface 弗瑞兹艾格有限及两合公司 2023-03-21 CN claimed
CN-110218282-B Process for preparing high solids polymer polyols having low viscosity 锦湖石油化学株式会社 2022-09-06 CN claimed
US-11434319-B2 Method of preparing high solids content polymer polyols having low viscosity KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2022-09-06 US claimed
CN-111032697-B In situ polymer blends for tires 盛禧奥欧洲有限责任公司 2022-07-05 CN claimed
EP-3294710-B1 MONOMER FOR COPOLYMERIZATION WITH ALKENES, DIENES, VINYL COMPOUNDS AND/OR VINYLIDENE COMPOUNDS, METHOD FOR THE SYNTHESIS OF A COPOLYMER, RUBBER MIXTURE AND USE THEREOF CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2022-01-12 EP claimed
CN-110218281-B Process for preparing monodisperse polymer polyols 锦湖石油化学株式会社 2022-01-11 CN claimed
CN-109312117-B Rubber composition 盛禧奥欧洲有限责任公司 2021-06-18 CN claimed
CN-109195810-B Tyre for vehicle wheels 倍耐力轮胎股份公司 2021-02-02 CN claimed
CN-107466307-B Polymer blend for tires 盛禧奥欧洲有限责任公司 2020-07-14 CN claimed
US-20190233624-A1 RUBBER MIXTURE, VULCANIZATE OF THE RUBBER MIXTURE, AND VEHICLE TIRES CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2019-08-01 US claimed
EP-3452518-A1 RUBBER MIXTURE, VULCANIZATE OF THE RUBBER MIXTURE, AND VEHICLE TIRES Continental Reifen Deutschland GmbH (DE) 2019-03-13 EP claimed
CN-109312117-A Rubber composition 盛禧奥欧洲有限责任公司 2019-02-05 CN claimed
EP-3294710-A1 MONOMER FOR COPOLYMERIZATION WITH ALKENES, DIENES, VINYL COMPOUNDS AND/OR VINYLIDENE COMPOUNDS, METHOD FOR THE SYNTHESIS OF A COPOLYMER, COPOLYMER, RUBBER MIXTURE AND USE THEREOF Continental Reifen Deutschland GmbH (DE) 2018-03-21 EP claimed
US-20180065928-A1 MONOMER FOR COPOLYMERIZATION WITH ALKENES, DIENES, VINYL COMPOUNDS AND/OR VINYLIDENE COMPOUNDS, METHOD FOR THE SYNTHESIS OF A COPOLYMER, COPOLYMER, RUBBER MIXTURE AND USE THEREOF CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2018-03-08 US claimed
CN-107466307-A Polymer blend for tires 盛禧奥欧洲有限责任公司 2017-12-12 CN claimed
US-9701809-B2 Rubber mixture and vehicle tire CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2017-07-11 US claimed
US-20160297948-A1 RUBBER MIXTURE AND VEHICLE TIRE CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2016-10-13 US claimed
EP-2886566-B1 Rubber composition and vehicle tyre CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2016-09-14 EP claimed
CN-102464767-A Method for in-situ preparation of silicone rubber composite material PETROCHINA CO LTD 2012-05-23 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065928-A1 MONOMER FOR COPOLYMERIZATION WITH ALKENES, DIENES, VINYL COMPOUNDS AND/OR VINYLIDENE COMPOUNDS, METHOD FOR THE SYNTHESIS OF A COPOLYMER, COPOLYMER, RUBBER MIXTURE AND USE THEREOF TMT1A, PAICS, STS ALDH1A1 120/4885TAS1R3 512/4885TAS1R1 212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.