SCHEMBL9324006

SCHEMBL9324006

C=Cc1ccc(COC(OCc2ccc(C=C)cc2)C(OCc2ccc(C=C)cc2)OCc2ccc(C=C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
HDAC8 Q9BY41 1/20 0.32
TAS1R3 Q7RTX0 2/20 0.31
TAS1R1 Q7RTX1 2/20 0.31
SLC1A3 P43003 2/20 0.31
SLC1A2 P43004 2/20 0.31
SLC1A1 P43005 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5199701 0.83 ALDH1A1 (0.44) ALDH1A1TSHRTDP1CHRNB2CHRNB4
SCHEMBL21156384 0.80 ALDH1A1 (0.41) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL5066935 0.79 ALDH1A1 (0.55) ALDH1A1TSHRTDP1CHRNB2CHRNB4
SCHEMBL4440288 0.79 ALDH1A1 (0.39) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL13275281 0.79 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL6310633 0.79 ALDH1A1 (0.39) ALDH1A1TSHRTDP1CHRNB2CHRNB4
SCHEMBL5069327 0.79 ALDH1A1 (0.39) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL1081809 0.79 ALDH1A1 (0.39) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL3957537 0.79 ALDH1A1 (0.39) ALDH1A1TSHRTDP1CHRNB2CHRNB4
SCHEMBL188152 0.77 ALDH1A1 (0.38) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0397802-B1 COMPLETE ETHER CAPPING OF OLIGOMERIC POLYPHENOLS ALLIED SIGNAL INC (US) 1994-01-19 EP disclosed
US-4871831-A Complete ether capping of oligomeric polyphenols ALLIED-SIGNAL INC. (US) 1989-10-03 US disclosed