SCHEMBL4440288

SCHEMBL4440288

C=Cc1ccc(COC(C)OC)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
RCE1 Q9Y256 1/20 0.36
TAS1R3 Q7RTX0 2/20 0.35
TAS1R1 Q7RTX1 2/20 0.35
TP53 P04637 2/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TRPA1 O75762 1/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
HIF1A Q16665 1/20 0.32
TSHR P16473 2/20 0.32
IDO1 P14902 2/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5199701 0.83 ALDH1A1 (0.44) ALDH1A1RCE1TAS1R3TAS1R1TP53
SCHEMBL4064511 0.82 PDCD1 (0.43) ALDH1A1TSHRSMN1; SMN2
SCHEMBL1359653 0.80 TP53 (0.41) ALDH1A1RCE1TP53TRPA1TSHR
SCHEMBL21156384 0.80 ALDH1A1 (0.41) ALDH1A1RCE1TAS1R3TAS1R1TP53
SCHEMBL9324006 0.79 ALDH1A1 (0.48) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL5069327 0.79 ALDH1A1 (0.39) ALDH1A1RCE1TAS1R3TAS1R1TP53
SCHEMBL6310633 0.79 ALDH1A1 (0.39) ALDH1A1RCE1TAS1R3TAS1R1TP53
SCHEMBL3957537 0.79 ALDH1A1 (0.39) ALDH1A1RCE1TAS1R3TAS1R1TP53
SCHEMBL1081809 0.79 ALDH1A1 (0.39) ALDH1A1RCE1TAS1R3TAS1R1TP53
SCHEMBL13469001 0.78 ADRB2 (0.35) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102924-A2 SEPARATION OF ELECTROLYTES IN LITHIUM BATTERIES SION POWER CORPORATION (US) 2009-09-23 EP disclosed
WO-2008070059-A2 SEPARATION OF ELECTROLYTES IN LITHIUM BATTERIES SION POWER CORPORATION (US) 2008-06-12 WO disclosed