Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FURIN | P09958 | 5/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24490420 | 0.90 | C3AR1 (0.34) | RENSMN1; SMN2FURINC3AR1SIRT5 | |
| SCHEMBL21915057 | 0.90 | C3AR1 (0.34) | RENSMN1; SMN2FURINC3AR1SIRT5 | |
| SCHEMBL22001947 | 0.90 | C3AR1 (0.34) | RENSMN1; SMN2FURINC3AR1SIRT5 | |
| SCHEMBL24703694 | 0.89 | SMN1; SMN2 (0.32) | RENSMN1; SMN2FURINC3AR1SIRT5 | |
| SCHEMBL25070715 | 0.87 | FURIN (0.31) | RENSMN1; SMN2FURINC3AR1SIRT5 | |
| SCHEMBL21914973 | 0.86 | SMN1; SMN2 (0.33) | RENSMN1; SMN2FURINC3AR1SIRT6 | |
| SCHEMBL23393940 | 0.85 | SIRT5 (0.39) | SMN1; SMN2FURINC3AR1SIRT5LMNA | |
| SCHEMBL20385879 | 0.85 | SMN1; SMN2 (0.39) | RENSMN1; SMN2FURINC3AR1SIRT6 | |
| SCHEMBL22045351 | 0.85 | FURIN (0.39) | RENSMN1; SMN2FURINC3AR1SIRT5 | |
| SCHEMBL17448412 | 0.85 | SMN1; SMN2 (0.34) | RENSMN1; SMN2FURINC3AR1SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017072662-A1 | ANTIBODY CONJUGATES COMPRISING TOLL-LIKE RECEPTOR AGONIST | NOVARTIS AG (CH) | 2017-05-04 | — | — | WO | disclosed |