Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | Q9HBH1 | 1/20 | 0.34 | |
| ▸ | FURIN | P09958 | 2/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001947 | 0.87 | C3AR1 (0.34) | SMN1; SMN2SIRT6SIRT1FURINC3AR1 | |
| SCHEMBL24490420 | 0.87 | C3AR1 (0.34) | SMN1; SMN2SIRT6SIRT1FURINC3AR1 | |
| SCHEMBL21915057 | 0.87 | C3AR1 (0.34) | SMN1; SMN2SIRT6SIRT1FURINC3AR1 | |
| SCHEMBL24172601 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2DPP7SIRT6SIRT1CA1 | |
| SCHEMBL21152822 | 0.86 | SIRT6 (0.44) | SMN1; SMN2DPP7SIRT6SIRT1FURIN | |
| SCHEMBL18818915 | 0.85 | REN (0.34) | SMN1; SMN2SIRT6SIRT1FURINC3AR1 | |
| SCHEMBL1711520 | 0.85 | C3AR1 (0.44) | SMN1; SMN2FURINNOD1C3AR1 | |
| SCHEMBL1711524 | 0.85 | C3AR1 (0.44) | SMN1; SMN2FURINNOD1C3AR1 | |
| SCHEMBL23393940 | 0.83 | SIRT5 (0.39) | SMN1; SMN2FURINNOD1C3AR1 | |
| SCHEMBL24571690 | 0.83 | FURIN (0.37) | SMN1; SMN2DPP7SIRT6SIRT1FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180200378-A1 | COMPOUNDS FOR TREATING CANCER | Bicyclerd Limited (GB) | 2018-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180200378-A1 | COMPOUNDS FOR TREATING CANCER | TP53, VHL, MYC | SMN1; SMN2 3956/4885DPP7 3309/4885SIRT6 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.