Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820563 | 1.00 | ALOX5 (0.44) | ALOX5ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL18820361 | 0.92 | ALDH1A1 (0.44) | ALOX5ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL18820369 | 0.89 | ALOX5 (0.49) | ALOX5ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL18820372 | 0.89 | ALOX5 (0.56) | ALOX5ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL18820523 | 0.89 | ALOX5 (0.45) | ALOX5ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL18820598 | 0.88 | ALDH1A1 (0.47) | ALOX5ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL18819920 | 0.88 | ALDH1A1 (0.54) | ALOX5ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL24990478 | 0.86 | ALDH1A1 (0.42) | ALOX5ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL22708080 | 0.86 | ALOX5 (0.40) | ALOX5ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL18820603 | 0.84 | ALOX5 (0.43) | ALOX5ALDH1A1HSD17B10HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11355714-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-06-07 | — | — | US | disclosed |
| US-20190058133-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-02-21 | — | — | US | disclosed |
| WO-2017071791-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11355714-B2 | Materials for organic electroluminescent devices | SLCO4C1, SLCO2A1, SLCO2B1 | ALOX5 1495/4885ALDH1A1 1315/4885HSD17B10 2582/4885 |
| US-20190058133-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO4C1, SLCO2A1, SLCO2B1 | ALOX5 1495/4885ALDH1A1 1315/4885HSD17B10 2582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.