Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 3/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820369 | 0.90 | ALOX5 (0.49) | ALOX5CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL18820372 | 0.90 | ALOX5 (0.56) | ALOX5CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL18820559 | 0.89 | ALOX5 (0.44) | ALOX5CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL18820563 | 0.89 | ALOX5 (0.44) | ALOX5CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL18820361 | 0.88 | ALDH1A1 (0.44) | ALOX5CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL18819920 | 0.86 | ALDH1A1 (0.54) | ALOX5CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL18820518 | 0.85 | ALOX5 (0.58) | ALOX5CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL18820524 | 0.83 | ALOX5 (0.49) | ALOX5CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL18820358 | 0.83 | ALOX5 (0.49) | ALOX5CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL23819588 | 0.80 | ALOX5 (0.38) | ALOX5CRHBPCRHR2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11355714-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-06-07 | — | — | US | disclosed |
| US-20190058133-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-02-21 | — | — | US | disclosed |
| WO-2017071791-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11355714-B2 | Materials for organic electroluminescent devices | SLCO4C1, SLCO2A1, SLCO2B1 | ALOX5 1495/4885CRHBP 3074/4885CRHR2 4459/4885 |
| US-20190058133-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO4C1, SLCO2A1, SLCO2B1 | ALOX5 1495/4885CRHBP 3074/4885CRHR2 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.