Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19386702 | 0.88 | SIRT6 (0.38) | SIRT6SIRT1FOLH1GNAI3GNAO1 | |
| SCHEMBL13707922 | 0.84 | FOLH1 (0.41) | SIRT6SIRT1FOLH1HPGDSGNAI3 | |
| SCHEMBL18457874 | 0.83 | GSR (0.40) | SIRT6SIRT1FOLH1HPGDSGNAI3 | |
| SCHEMBL23330464 | 0.78 | FOLH1 (0.35) | SIRT6SIRT1FOLH1HPGDSGSR | |
| SCHEMBL25944730 | 0.77 | CASP2 (0.49) | SIRT6SIRT1SLC6A5TLR2DPP7 | |
| SCHEMBL2248012 | 0.77 | GABRP (0.44) | FOLH1HPGDSGSRCA1CA12 | |
| SCHEMBL15834023 | 0.77 | FOLH1 (0.45) | SIRT6SIRT1FOLH1HPGDSGNAI3 | |
| SCHEMBL2547160 | 0.76 | ANPEP (0.51) | CPB2TLR2 | |
| SCHEMBL13416824 | 0.76 | FOLH1 (0.43) | SIRT6SIRT1FOLH1HPGDSGNAI3 | |
| SCHEMBL1262904 | 0.76 | FOLH1 (0.43) | SIRT6SIRT1FOLH1HPGDSGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170119907-A1 | Targeted Therapeutics | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119907-A1 | Targeted Therapeutics | ANXA3, ANXA5, ANXA6 | SIRT6 2958/4885SIRT1 4333/4885FOLH1 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.