Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.54 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18824235 | 0.95 | DRD2 (0.50) | DRD2CACNA1HSIGMAR1MAOAMAOB | |
| SCHEMBL31301242 | 0.89 | DRD2 (0.63) | DRD2CACNA1HSIGMAR1TDP1CD274 | |
| SCHEMBL15859325 | 0.87 | DRD2 (0.55) | DRD2CACNA1HSIGMAR1TDP1ACKR3 | |
| SCHEMBL31496727 | 0.85 | DRD2 (0.56) | DRD2CACNA1HSIGMAR1MAOAMAOB | |
| SCHEMBL13202614 | 0.84 | DRD2 (0.59) | DRD2CACNA1HSIGMAR1TDP1CD274 | |
| Hydrochloric Acid SCHEMBL25170707 | 0.84 | DRD2 (0.55) | DRD2CACNA1HSIGMAR1MAOAMAOB | |
| SCHEMBL5324032 | 0.83 | DRD2 (0.57) | DRD2CACNA1HSIGMAR1TDP1CD274 | |
| SCHEMBL18390128 | 0.83 | DRD2 (0.57) | DRD2CACNA1HSIGMAR1TDP1CD274 | |
| SCHEMBL31301250 | 0.83 | DRD2 (0.56) | DRD2CACNA1HSIGMAR1TDP1CD274 | |
| SCHEMBL24172673 | 0.83 | DRD2 (0.56) | DRD2CACNA1HSIGMAR1TDP1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180312493-A1 | Antibiotic Compounds, Pharmaceutical Formulations Thereof And Methods And Uses Therefor | CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2018-11-01 | — | — | US | disclosed |
| WO-2017075694-A1 | ANTIBIOTIC COMPOUNDS, PHARMACEUTICAL FORMULATIONS THEREOF AND METHODS AND USES THEREFOR | SIMON FRASER UNIVERSITY (CA) | 2017-05-11 | — | — | WO | disclosed |
| WO-2017075694-A1 | ANTIBIOTIC COMPOUNDS, PHARMACEUTICAL FORMULATIONS THEREOF AND METHODS AND USES THEREFOR | SIMON FRASER UNIVERSITY (CA) | 2017-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312493-A1 | Antibiotic Compounds, Pharmaceutical Formulations Thereof And Methods And Uses Therefor | UGT1A8, CYP2C8, CXCL8 | DRD2 4251/4885CACNA1H 4003/4885SIGMAR1 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.