Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12660103 | 0.86 | ADORA2A (0.63) | ADORA2AADORA1 | |
| SCHEMBL1883908 | 0.82 | ADORA2A (0.70) | ADORA2AADORA1 | |
| SCHEMBL6857591 | 0.81 | ADORA1 (0.65) | ADORA2AADORA1 | |
| SCHEMBL1882224 | 0.81 | ADORA2A (0.63) | ADORA2AADORA1 | |
| SCHEMBL1891524 | 0.79 | ADORA2A (0.49) | ADORA2AADORA1 | |
| SCHEMBL1880456 | 0.79 | ADORA2A (0.60) | ADORA2AADORA1 | |
| SCHEMBL12660096 | 0.79 | ADORA2A (0.70) | ADORA2AADORA1 | |
| SCHEMBL1881060 | 0.78 | ADORA1 (0.57) | ADORA2AADORA1 | |
| SCHEMBL1877439 | 0.78 | ADORA2A (0.59) | ADORA2AADORA1 | |
| SCHEMBL1879453 | 0.77 | ADORA2A (0.61) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105541-A1 | ALKYL SUBSTITUTED ARYLINDENOPYRIMIDINES AND THEIR USE AS HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105541-A1 | ALKYL SUBSTITUTED ARYLINDENOPYRIMIDINES AND THEIR USE AS HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONISTS | ADORA2A, ADORA3, ADORA2B | ADORA2A 1/4885ADORA1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.