SCHEMBL18826331

SCHEMBL18826331

CC(C)(C)C(=O)OC1Cc2cccc3cccc1c23

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 11/20 0.47
MTNR1B P49286 11/20 0.47
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2740796 0.88 MTNR1A (0.46) MTNR1AMTNR1BKDM4E
SCHEMBL10267902 0.85 MTNR1A (0.52) MTNR1AMTNR1BKDM4E
SCHEMBL21136912 0.83 MTNR1A (0.46) MTNR1AMTNR1BKDM4E
SCHEMBL19645628 0.83 LMNA (0.41) LMNAMAPTNPSR1
SCHEMBL14750838 0.83 MTNR1A (0.42) MTNR1AMTNR1BKDM4E
SCHEMBL16943708 0.82 MTNR1A (0.50) MTNR1AMTNR1BKDM4E
SCHEMBL21117245 0.82 MTNR1A (0.46) MTNR1AMTNR1BKDM4E
SCHEMBL19335458 0.80 MTNR1A (0.37) MTNR1AMTNR1BKDM4E
SCHEMBL20306559 0.80 MTNR1A (0.48) MTNR1AMTNR1BKDM4E
SCHEMBL2776949 0.80 MTNR1A (0.48) MTNR1AMTNR1BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007178-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-26 US disclosed
US-9869931-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-16 US disclosed
US-9846360-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-19 US disclosed
US-9645498-B2 Developer and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-09 US disclosed