SCHEMBL1882899

SCHEMBL1882899

CCC/C=C/c1ccccc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.46
ALDH1A1 P00352 4/20 0.45
TSHR P16473 3/20 0.45
RAB9A P51151 5/20 0.42
KDM4E B2RXH2 5/20 0.42
APOBEC3A P31941 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
MEN1 O00255 1/20 0.41
PABPC1 P11940 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP1A2 P05177 2/20 0.39
TP53 P04637 1/20 0.39
CYP2D6 P10635 1/20 0.39
THPO P40225 1/20 0.39
HIF1A Q16665 1/20 0.39
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
PTGER1 P34995 1/20 0.38
PTGER4 P35408 1/20 0.38
PTGER3 P43115 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1882900 1.00 TLR8 (0.46) TLR8ALDH1A1TSHRRAB9AKDM4E
SCHEMBL20524537 0.88 PDE5A (0.44) TLR8ALDH1A1TSHRRAB9AKDM4E
SCHEMBL27431004 0.88 PDE5A (0.44) TLR8ALDH1A1TSHRRAB9AKDM4E
SCHEMBL8206128 0.87 TLR8 (0.51) TLR8MEN1KMT2APTGER1PTGER4
SCHEMBL29101283 0.86 CYSLTR2 (0.46) TLR8ALDH1A1TSHRRAB9AKDM4E
SCHEMBL9244066 0.85 PDE5A (0.41) TLR8ALDH1A1RAB9AKDM4EAPOBEC3A
SCHEMBL29373824 0.83 ALDH1A1 (0.48) ALDH1A1TSHRRAB9AKDM4EAPOBEC3A
SCHEMBL1276606 0.83 ALDH1A1 (0.48) ALDH1A1TSHRRAB9AKDM4EAPOBEC3A
SCHEMBL2313488 0.83 ALDH1A1 (0.48) ALDH1A1TSHRRAB9AKDM4EAPOBEC3A
SCHEMBL6547635 0.82 TLR8 (0.43) TLR8ALDH1A1TSHRRAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1849758-B1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORP (KR) 2009-03-25 EP claimed
EP-1849758-A1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst Hyosung Corporation (KR) 2007-10-31 EP claimed
US-20070232842-A1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst HYOSUNG CORPORATION (KR) 2007-10-04 US claimed
WO-2004058666-A1 PREPARATION METHOD OF 1,5-DIMETHYLTETRALIN HYOSUNG CORPORATION (KR) 2004-07-15 WO claimed
EP-0926114-B1 Crystallization of 2,6-Dimethylnaphthalene BP CORP NORTH AMERICA INC (US) 2004-05-19 EP claimed
EP-1047654-A1 METHOD FOR PRODUCING 2,6-DMN FROM MIXED DIMETHYLNAPHTHALENES BY CRYSTALLIZATION, ADSORPTION AND ISOMERIZATION Chevron Chemical Company LLC (US) 2000-11-02 EP claimed
US-6057487-A PRECIPITATION AND SEPARATION SUPERNATANT WITH 2,6-DIMETHYLNAPHTHALENE CHEVRON CHEMICAL COMPANY (US) 2000-05-02 US claimed
EP-0687248-B1 CRYSTALLIZATION OF 2,6-DIMETHYLNAPHTHALENE AMOCO CORP (US) 1999-10-20 EP claimed
WO-1999033770-A1 METHOD FOR PRODUCING 2,6-DMN FROM MIXED DIMETHYLNAPHTHALENES BY CRYSTALLIZATION, ADSORPTION AND ISOMERIZATION CHEVRON CHEMICAL COMPANY LLC (US) 1999-07-08 WO claimed
EP-0594856-B1 PROCESS FOR PRODUCING DIALKYLNAPHTHALENE TEIJIN LTD (JP) 1997-04-02 EP claimed
US-5365001-A Catalytic cyclization of alkenebenzene in the presence of hydrogen TEIJIN LIMITED (JP) 1994-11-15 US claimed
EP-0594856-A1 PROCESS FOR PRODUCING DIALKYLNAPHTHALENE TEIJIN LIMITED (JP) 1994-05-04 EP claimed
JP-7033688-A None JP disclosed
US-11306041-B2 Catalytic synthesis of super linear alkenyl arenes using rhodium catalysts UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2022-04-19 US disclosed
US-20210163377-A1 CATALYTIC SYNTHESIS OF SUPER LINEAR ALKENYL ARENES USING RHODIUM CATALYSTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2021-06-03 US disclosed
WO-2018183916-A1 CATALYTIC SYNTHESIS OF SUPER LINEAR ALKENYL ARENES USING RHODIUM CATALYSTS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2018-10-04 WO disclosed
EP-0636597-A1 Process for producing monoalkenyl aromatic hydrocarbon compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-02-01 EP disclosed
US-5334796-A Alkenylation an olefinic compound in presence of an ultrasound irradiated eutectic alkali metal and an activators AMOCO CORPORATION (US) 1994-08-02 US disclosed
US-5198594-A Alkylation of alkylaromatics promoted by sonicated alkali metal AMOCO CORPORATION (US) 1993-03-30 US disclosed
US-3997616-A FROM ALKENYLBENZENE, CYCLIZATION CATALYST TEIJIN LIMITED (JA) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163377-A1 CATALYTIC SYNTHESIS OF SUPER LINEAR ALKENYL ARENES USING RHODIUM CATALYSTS MSMO1, CYP2E1, PNMT TLR8 3927/4885ALDH1A1 2038/4885TSHR 3693/4885
US-20070232842-A1 Preparation method of 1,5-dimethyltetralin using dealuminated zeolite beta catalyst DERA, DIMT1, MGST1 TLR8 4023/4885ALDH1A1 2043/4885TSHR 4415/4885
US-11306041-B2 Catalytic synthesis of super linear alkenyl arenes using rhodium catalysts MSMO1, CYP2E1, PNMT TLR8 3927/4885ALDH1A1 2038/4885TSHR 3693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.