SCHEMBL6547635

SCHEMBL6547635

CCC/C=C/c1cccc(C)c1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.43
PTGER1 P34995 2/20 0.39
PTGER4 P35408 2/20 0.39
PTGER3 P43115 2/20 0.39
PTGER2 P43116 2/20 0.39
CXCR5 P32302 2/20 0.38
FABP4 P15090 1/20 0.35
RET P07949 1/20 0.35
ALDH1A1 P00352 3/20 0.33
CASP1 P29466 1/20 0.33
TSHR P16473 1/20 0.33
CYSLTR2 Q9NS75 2/20 0.33
CYSLTR1 Q9Y271 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547166 0.86 PTGER1 (0.38) PTGER1PTGER4PTGER3PTGER2FABP4
SCHEMBL1882899 0.82 TLR8 (0.46) TLR8PTGER1PTGER4PTGER3PTGER2
SCHEMBL1882900 0.82 TLR8 (0.46) TLR8PTGER1PTGER4PTGER3PTGER2
SCHEMBL6441235 0.81 PTGER1 (0.40) PTGER1PTGER4PTGER3PTGER2FABP4
SCHEMBL8206128 0.78 TLR8 (0.51) TLR8PTGER1PTGER4PTGER3PTGER2
SCHEMBL1469238 0.77 TLR8 (0.43) TLR8
SCHEMBL1469236 0.77 TLR8 (0.43) TLR8
SCHEMBL6546806 0.77 PTGS1 (0.40) FABP4RETALDH1A1CASP1TSHR
SCHEMBL6546792 0.77 PTGS1 (0.40) FABP4RETALDH1A1CASP1TSHR
SCHEMBL6546663 0.75 TLR8 (0.46) TLR8CXCR5ALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed