Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21143280 | 0.87 | KMT2A (0.49) | KMT2AMEN1ATMTSHRAPAF1 | |
| SCHEMBL18422110 | 0.81 | KMT2A (0.47) | KMT2AMEN1ATMTSHRAPAF1 | |
| SCHEMBL434230 | 0.79 | HTT (0.49) | KMT2AMEN1ATMTSHRSMN1; SMN2 | |
| SCHEMBL21896917 | 0.76 | CTSS (0.44) | KMT2AMEN1ATMTSHRAPAF1 | |
| SCHEMBL19333959 | 0.74 | APAF1 (0.49) | KMT2AMEN1ATMAPAF1SMN1; SMN2 | |
| SCHEMBL306216 | 0.74 | APAF1 (0.49) | KMT2AMEN1ATMAPAF1SMN1; SMN2 | |
| SCHEMBL536302 | 0.74 | APAF1 (0.49) | KMT2AMEN1ATMAPAF1SMN1; SMN2 | |
| SCHEMBL14015971 | 0.74 | MTOR (0.52) | KMT2AMEN1TSHRAPAF1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL304495 | 0.73 | APAF1 (0.47) | KMT2AMEN1ATMAPAF1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2552987 | 0.73 | APAF1 (0.47) | KMT2AMEN1ATMAPAF1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640719-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-05-10 | — | — | EP | disclosed |