Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18829280 | 0.87 | KMT2A (0.44) | KMT2AMEN1TSHRATMAPAF1 | |
| SCHEMBL18422110 | 0.86 | KMT2A (0.47) | KMT2AMEN1TSHRATMAPAF1 | |
| SCHEMBL21896917 | 0.81 | CTSS (0.44) | KMT2AMEN1TSHRATMAPAF1 | |
| SCHEMBL10906098 | 0.79 | NAALAD2 (0.49) | KMT2AMEN1ATMAPAF1NAALAD2 | |
| SCHEMBL19333959 | 0.79 | APAF1 (0.49) | KMT2AMEN1ATMAPAF1SMN1; SMN2 | |
| SCHEMBL536302 | 0.79 | APAF1 (0.49) | KMT2AMEN1ATMAPAF1SMN1; SMN2 | |
| SCHEMBL306216 | 0.79 | APAF1 (0.49) | KMT2AMEN1ATMAPAF1SMN1; SMN2 | |
| SCHEMBL14015971 | 0.79 | MTOR (0.52) | KMT2AMEN1TSHRAPAF1ALDH1A1 | |
| SCHEMBL434230 | 0.78 | HTT (0.49) | KMT2AMEN1TSHRATMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL304495 | 0.78 | APAF1 (0.47) | KMT2AMEN1ATMAPAF1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10344019-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344019-B2 | Antiviral compounds | MAVS, EIF2AK2, ZC3HAV1 | KMT2A 3803/4885MEN1 4292/4885TSHR 4853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.