SCHEMBL1882971

SCHEMBL1882971

Cc1cc(Cl)c(Cl)c(O)c1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.55
HPGD P15428 6/20 0.55
TSHR P16473 6/20 0.55
CASP1 P29466 1/20 0.55
SIRT1 Q96EB6 1/20 0.48
CYP3A4 P08684 6/20 0.44
MAPK1 P28482 2/20 0.44
CHRM1 P11229 2/20 0.44
ALOX15 P16050 2/20 0.44
TBXA2R P21731 2/20 0.44
ADRA1A P35348 2/20 0.44
HTR2B P41595 2/20 0.44
MAOA P21397 1/20 0.44
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
ALDH1A1 P00352 4/20 0.39
MAPT P10636 2/20 0.39
GAA P10253 1/20 0.39
HSP90AA1 P07900 2/20 0.39
RECQL P46063 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10769365 0.82 HSD17B10 (0.65) HSD17B10HPGDTSHRCASP1SIRT1
SCHEMBL25929818 0.82 SIRT1 (0.45) HSD17B10HPGDTSHRCASP1SIRT1
SCHEMBL2049441 0.82 CYP3A4 (0.52) HSD17B10HPGDTSHRCASP1SIRT1
SCHEMBL11434164 0.82 SIRT1 (0.41) HSD17B10HPGDTSHRCASP1SIRT1
SCHEMBL736999 0.80 HSD17B10 (0.50) HSD17B10HPGDTSHRCASP1SIRT1
SCHEMBL11038441 0.80 ALDH1A1 (0.48) HSD17B10HPGDTSHRCASP1SIRT1
SCHEMBL157574 0.80 SIRT1 (0.48) HSD17B10HPGDTSHRCASP1SIRT1
SCHEMBL212921 0.80 HSD17B10 (0.55) HSD17B10HPGDTSHRCASP1SIRT1
SCHEMBL10590391 0.77 HSD17B10 (0.59) HSD17B10HPGDTSHRCASP1SIRT1
SCHEMBL31120437 0.76 CYP3A4 (0.40) HSD17B10HPGDTSHRCASP1SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376402-A1 ANTIMICROBIAL COMPOSITION AND THE FORMULATION COMPRISING THE SAME SPECIALTY OPERATIONS FRANCE (FR) 2024-11-14 US claimed
EP-4398725-A1 ANTIMICROBIAL COMPOSITION AND THE FORMULATION COMPRISING THE SAME SPECIALTY OPERATIONS FRANCE (FR) 2024-07-17 EP claimed
CN-118055697-A Antimicrobial composition and formulation comprising the same 法国特种经营公司 2024-05-17 CN claimed
CN-117887529-A Solid aromatherapy toilet cleaner and preparation method thereof 威莱(广州)日用品有限公司 2024-04-16 CN claimed
CN-115024984-B Preparation method of porcelain tooth restoration pretreatment agent 佛山铂瑞天辰医疗器械科技有限公司 2023-08-22 CN claimed
WO-2023036940-A1 ANTIMICROBIAL COMPOSITION AND THE FORMULATION COMPRISING THE SAME RHODIA OPERATIONS (FR) 2023-03-16 WO claimed
CN-115024984-A Preparation method of pretreatment agent for porcelain tooth repair 佛山(华南)新材料研究院 2022-09-09 CN claimed
CN-113122944-B Functional finished clothes 北京卓文时尚纺织股份有限公司 2022-05-31 CN claimed
CN-113122944-A Functional finished clothes 北京卓文时尚纺织股份有限公司 2021-07-16 CN claimed
EP-3263145-B1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS BECTON DICKINSON CO (US) 2021-01-20 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
CN-1938072-A Method for the production and filter obtained using said method, comprising a nonwoven and/or filter injector structure or sheet and used for filtering and removing legionella pneumophila from any equipment at risk of its proliferation JOAQUIN ESPUELAS PENALVA (ES) 2007-03-28 CN claimed
CN-1636474-A Antibacterial elastic soft article and method of manufacture CHOU BELLE L (US) 2005-07-13 CN claimed
EP-1537796-A2 Anti-microbial elastomeric flexible article, such as a glove, and manufacturing method Chou, Belle L. (US) 2005-06-08 EP claimed
US-20050112180-A1 Antimicrobial elastomeric flexible article and manufacturing method SHEN WEI (USA) INC. 2005-05-26 US claimed
EP-1157708-A2 Anti-microbial surgical devices ETHICON, INC. (US) 2001-11-28 EP claimed
EP-0480189-B1 Pharmaceutical compositions for topical use comprising hyaluronic acid sodium salt and disinfectant substances ALTERGON SA (CH) 1996-03-20 EP claimed
EP-0480189-A1 Pharmaceutical compositions for topical use comprising hyaluronic acid sodium salt and disinfectant substances ALTERGON S.A. (CH) 1992-04-15 EP claimed
US-4468508-A Glycidyl ether of novolak type substituted phenolic resin, process for producing the same, and encapsulating compound composed mainly of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-08-28 US claimed