Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1883069

N.O=C(CCCO)OCCO

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.49
DGKA P23743 1/20 0.46
CAMK2A Q9UQM7 1/20 0.42
TSHR P16473 2/20 0.39
ADRA2A P08913 1/20 0.39
ADRA1A P35348 1/20 0.39
DNM1 Q05193 1/20 0.38
MAPT P10636 1/20 0.38
BLM P54132 1/20 0.38
CYP1A2 P05177 1/20 0.37
ACHE P22303 1/20 0.36
EPHX2 P34913 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
GPR84 Q9NQS5 1/20 0.33
KDM4E B2RXH2 1/20 0.33
DUSP3 P51452 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13818881 0.97 MGLL (0.50) MGLLDGKACAMK2ATSHRADRA2A
Ammonia Solution, Strong SCHEMBL27661106 0.92 DGKA (0.54) MGLLDGKATSHRADRA2AADRA1A
SCHEMBL822209 0.90 DGKA (0.52) MGLLDGKATSHRADRA2AADRA1A
SCHEMBL206255 0.90 DGKA (0.56) MGLLDGKATSHRADRA2AADRA1A
SCHEMBL822152 0.90 MGLL (0.52) MGLLDGKATSHRADRA2AADRA1A
SCHEMBL822217 0.88 DGKA (0.56) MGLLDGKATSHRADRA2AADRA1A
SCHEMBL299576 0.88 DGKA (0.56) MGLLDGKATSHRADRA2AADRA1A
SCHEMBL821826 0.88 DGKA (0.56) MGLLDGKATSHRADRA2AADRA1A
SCHEMBL821541 0.88 DGKA (0.56) MGLLDGKATSHRADRA2AADRA1A
SCHEMBL275281 0.88 DGKA (0.56) MGLLDGKATSHRADRA2AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6884835-B2 Process for making light weight rubber composition containing clay THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-04-26 US claimed
US-20040162379-A1 Light weight rubber composition containing clay THE GOODYEAR TIRE & RUBBER COMPANY 2004-08-19 US claimed
US-6727311-B2 TIRE TRANSMISSION BELTS, TIRES THE GOODYEAR TIRE & RUBBER COMPANY 2004-04-27 US claimed
US-20030144401-A1 Nanocomposite of elastomer and dispersion therein of intercalated clay prepared in an aqueous medium with functional elastomer GOODYEAR TIRE & RUBBER COMPANY, THE 2003-07-31 US claimed
US-20030004250-A1 Light weight rubber composition containing clay GOODYEAR TIRE & RUBBER COMPANY, THE 2003-01-02 US claimed
US-7935184-B2 Method of preparing imidazolium surfactants BRIDGESTONE CORPORATION (JP) 2011-05-03 US disclosed
US-7601772-B2 Nano-composite and method thereof BRIDGESTONE CORPORATION 2009-10-13 US disclosed
WO-2007149842-A2 METHOD OF PREPARING IMIDAZOLIUM SURFACTANTS BRIDGESTONE CORPORATION (JP) 2007-12-27 WO disclosed
US-20070293684-A1 Method of preparing imidazolium surfactants BRIDGESTONE CORPORATION 2007-12-20 US disclosed
US-20070161734-A1 Comprising clay and cationic mediator such as imidazolium compound wherein cationic mediator comprises hydrophobic unit and cationic unit; use in preparing products such as tires with improved and well-balanced properties including gas impermeability, cure rates, and superior mechanical characteristics BRIDGESTONE CORPORATION (JP) 2007-07-12 US disclosed
US-7055566-B2 Light weight rubber composition containing clay THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-06-06 US disclosed
US-6884835-B2 Process for making light weight rubber composition containing clay THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-04-26 US disclosed
US-20050020753-A1 Light weight rubber composition containing clay THE GOODYEAR TIRE & RUBBER COMPANY 2005-01-27 US disclosed
US-20040162379-A1 Light weight rubber composition containing clay THE GOODYEAR TIRE & RUBBER COMPANY 2004-08-19 US disclosed
US-6759464-B2 FUNCTIONALIZED ELASTOMERS WITH INTERCALCATED AND PARTIALLY EXFOLIATED, SWELLABLE CLAY; TIRE TREAD, SIDEWALL AND/OR INNERLINER THE GOODYEAR TIRE & RUBBER COMPANY 2004-07-06 US disclosed
US-6727311-B2 TIRE TRANSMISSION BELTS, TIRES THE GOODYEAR TIRE & RUBBER COMPANY 2004-04-27 US disclosed
US-20030144401-A1 Nanocomposite of elastomer and dispersion therein of intercalated clay prepared in an aqueous medium with functional elastomer GOODYEAR TIRE & RUBBER COMPANY, THE 2003-07-31 US disclosed
US-20030004250-A1 Light weight rubber composition containing clay GOODYEAR TIRE & RUBBER COMPANY, THE 2003-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293684-A1 Method of preparing imidazolium surfactants SMARCC2, SMARCC1, ITPR3 MGLL 780/4885DGKA 1607/4885CAMK2A 3838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.