Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1889459 | 0.86 | HRH3 (0.31) | — | |
| SCHEMBL19130279 | 0.85 | HRH3 (0.34) | — | |
| Bromide SCHEMBL1882250 | 0.83 | SIGMAR1 (0.34) | — | |
| Bromide SCHEMBL30353850 | 0.82 | ALDH1A1 (0.34) | — | |
| Bromide SCHEMBL1882150 | 0.82 | CRHR1 (0.32) | — | |
| SCHEMBL17447703 | 0.82 | HRH3 (0.33) | — | |
| Bromide SCHEMBL1884304 | 0.81 | ALDH1A1 (0.36) | — | |
| SCHEMBL16206227 | 0.81 | SIGMAR1 (0.35) | — | |
| Bromide SCHEMBL1881355 | 0.81 | ALDH1A1 (0.33) | — | |
| Bromide SCHEMBL1885379 | 0.81 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9260397-B2 | Salts comprising aryl-alkyl-substituted imidazolium and triazolium cations and the use thereof | TECHNISCHE UNIVERSITAET DRESDEN (DE) | 2016-02-16 | — | — | US | disclosed |
| US-20110105761-A1 | Salts Comprising Aryl-Alkyl-Substituted Imidazolium and Triazolium Cations and the Use Thereof | TECHNISCHE UNIVERSITAET DRESDEN (DE) | 2011-05-05 | — | — | US | disclosed |