SCHEMBL18831745

SCHEMBL18831745

Cc1cc(C(C)c2ccc(OC(C)(C)C)c(C)c2)ccc1OC(=O)c1ccc(Oc2ccc(C(=O)C(C)(C)C)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TP53 P04637 1/20 0.35
GAA P10253 1/20 0.35
THRB P10828 1/20 0.35
KMT2A Q03164 4/20 0.34
MAPT P10636 1/20 0.34
PPARG P37231 3/20 0.33
PPARD Q03181 3/20 0.33
PPARA Q07869 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
ELANE P08246 1/20 0.33
NPC1 O15118 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.32
PRSS1 P07477 1/20 0.32
ACR P10323 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13751684 0.91 VDR (0.35) ALDH1A1TP53GAATHRBKMT2A
SCHEMBL13191290 0.90 TAS1R3 (0.33) ALDH1A1TP53GAATHRBKMT2A
SCHEMBL21168188 0.86 ELANE (0.32) ALDH1A1PPARGPPARDPPARAELANE
SCHEMBL12942489 0.84 TAS1R3 (0.33) ALDH1A1TP53GAATHRBKMT2A
SCHEMBL19139144 0.84 TAS1R3 (0.33) ALDH1A1TP53GAATHRBKMT2A
SCHEMBL21387331 0.83 MAPT (0.41) ALDH1A1KMT2AMAPTELANECYP3A4
SCHEMBL15499183 0.83 TAS1R3 (0.33) ALDH1A1TP53GAATHRBKMT2A
SCHEMBL12942435 0.82 MAPT (0.36) ALDH1A1MAPTPPARGPPARDPPARA
SCHEMBL18994759 0.82 PRSS1 (0.42) ALDH1A1GAAKMT2AMAPTCYP1A2
SCHEMBL13660382 0.81 ELANE (0.33) ALDH1A1TP53GAATHRBPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230056801-A1 Electrophotographic Photoreceptor, Electrophotographic Photoreceptor Cartridge, and Image Forming Device MITSUBISHI CHEMICAL CORPORATION (JP) 2023-02-23 US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed
EP-3165518-A1 TRIARYLAMINE DERIVATIVE, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER Kyocera Document Solutions Inc. (JP) 2017-05-10 EP disclosed