Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831547 | 0.91 | MAOA (0.37) | MRGPRX4SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL18831506 | 0.88 | LMNA (0.34) | MRGPRX4SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL20686857 | 0.86 | MRGPRX4 (0.47) | SLC22A12MRGPRX4SMN1; SMN2THRBNPC1 | |
| SCHEMBL18831587 | 0.86 | MRGPRX4 (0.37) | MRGPRX4MAOA | |
| SCHEMBL18831656 | 0.85 | GRM5 (0.38) | MRGPRX4SMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL18831482 | 0.85 | MRGPRX4 (0.36) | MRGPRX4SMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL18831366 | 0.85 | SLC22A12 (0.33) | SLC22A12MRGPRX4SMN1; SMN2HSP90AA1 | |
| SCHEMBL22038181 | 0.84 | PTGER1 (0.38) | SLC22A12SMN1; SMN2THRBALDH1A1HPGD | |
| SCHEMBL21317982 | 0.84 | SLC22A12 (0.41) | SLC22A12MRGPRX4MAPTRAB9ASGMS2 | |
| SCHEMBL19987601 | 0.84 | MRGPRX4 (0.44) | MRGPRX4SMN1; SMN2HSP90AA1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900655-B1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2017-05-10 | — | — | EP | disclosed |