Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831547 | 0.85 | MAOA (0.37) | MRGPRX4HTTMAOANPC1ALDH1A1 | |
| SCHEMBL18831746 | 0.84 | SLC22A12 (0.37) | MRGPRX4HTTHSP90AA1MAOANPC1 | |
| SCHEMBL18831506 | 0.83 | LMNA (0.34) | MRGPRX4HTTMAOANPC1ALDH1A1 | |
| SCHEMBL18831587 | 0.80 | MRGPRX4 (0.37) | MRGPRX4MAOA | |
| SCHEMBL23506126 | 0.76 | SMN1; SMN2 (0.47) | MAOAFFAR1NPC1ALDH1A1MAPT | |
| SCHEMBL18831522 | 0.76 | ALPL (0.36) | MRGPRX4HSP90AA1 | |
| SCHEMBL23506206 | 0.75 | FFAR4 (0.42) | PTGDR2FFAR1FFAR4ALDH1A1MAPT | |
| SCHEMBL20686643 | 0.75 | MRGPRX4 (0.41) | MRGPRX4HTTNPC1ALDH1A1MAPT | |
| SCHEMBL18831366 | 0.75 | SLC22A12 (0.33) | MRGPRX4HSP90AA1FFAR4SMN1; SMN2 | |
| SCHEMBL18831656 | 0.75 | GRM5 (0.38) | MRGPRX4TP53ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |