Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831883 | 0.81 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL18842297 | 0.80 | ALDH1A1 (0.43) | MEN1THRBKMT2AALDH1A1CYP3A4 | |
| SCHEMBL27920639 | 0.76 | ALDH1A1 (0.42) | MEN1THRBKMT2AALDH1A1CYP3A4 | |
| SCHEMBL18842298 | 0.76 | CYP3A4 (0.40) | MEN1THRBKMT2AALDH1A1CYP3A4 | |
| SCHEMBL15928735 | 0.74 | S100B (0.56) | MEN1THRBKMT2AALDH1A1CYP3A4 | |
| SCHEMBL24073825 | 0.73 | GAK (0.45) | CTSBCTSSCTSKMEN1THRB | |
| SCHEMBL15928736 | 0.72 | S100B (0.59) | MEN1THRBKMT2AALDH1A1CYP3A4 | |
| SCHEMBL30595859 | 0.71 | MAPT (0.58) | MEN1THRBKMT2AALDH1A1CYP3A4 | |
| SCHEMBL1527171 | 0.71 | MAPT (0.58) | MEN1THRBKMT2AALDH1A1CYP3A4 | |
| SCHEMBL2762254 | 0.70 | ALDH1A1 (0.44) | MEN1THRBKMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3165530-A1 | SPIROCYCLIC ARYL PHOSPHORUS OXIDE AND ARYL PHOSPHORUS SULFIDE | Qilu Pharmaceutical Co., Ltd (CN) | 2017-05-10 | — | — | EP | disclosed |