Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18832654 | 0.92 | LPAR1 (0.63) | LPAR1PDE4DSMPD1HDAC1HDAC8 | |
| SCHEMBL18832678 | 0.91 | LPAR1 (0.63) | LPAR1PDE4DSMPD1HDAC1HDAC8 | |
| SCHEMBL1561397 | 0.90 | LPAR1 (0.69) | LPAR1PDE4DSCDSMPD1HDAC1 | |
| SCHEMBL18832674 | 0.88 | LPAR1 (0.60) | LPAR1PDE4DSMPD1HDAC1HDAC8 | |
| SCHEMBL18832665 | 0.86 | LPAR1 (0.58) | LPAR1PDE4DSMPD1HDAC1HDAC8 | |
| SCHEMBL18832661 | 0.84 | LPAR1 (0.60) | LPAR1CXCR5 | |
| SCHEMBL18832655 | 0.83 | LPAR1 (0.53) | LPAR1PDE4DSMPD1HDAC1HDAC8 | |
| SCHEMBL18832667 | 0.82 | LPAR1 (0.53) | LPAR1MEN1KMT2A | |
| SCHEMBL18832675 | 0.82 | LPAR1 (0.61) | LPAR1NPC1RAB9AMEN1KMT2A | |
| Fipaxalparant SCHEMBL29398637 | 0.81 | LPAR1 (0.78) | LPAR1PDE4DSMPD1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | claimed |