Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561333 | 0.88 | LPAR1 (0.68) | LPAR1GPR132 | |
| SCHEMBL18832654 | 0.86 | LPAR1 (0.63) | LPAR1 | |
| SCHEMBL18832656 | 0.86 | LPAR1 (0.54) | LPAR1F10SIRT2ALOX5GPR132 | |
| SCHEMBL18832675 | 0.83 | LPAR1 (0.61) | LPAR1KMT2ABRD4SIRT2MEN1 | |
| SCHEMBL18832664 | 0.83 | LPAR1 (0.58) | LPAR1LMNASMN1; SMN2SIRT2HPGD | |
| SCHEMBL18832662 | 0.82 | LPAR1 (0.60) | LPAR1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL18832661 | 0.82 | LPAR1 (0.60) | LPAR1LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18832660 | 0.82 | LPAR1 (0.59) | LPAR1KMT2AMEN1 | |
| SCHEMBL18832657 | 0.82 | LPAR1 (0.79) | LPAR1KMT2AF10SIRT2MEN1 | |
| SCHEMBL18832658 | 0.81 | LPAR1 (0.58) | LPAR1HPGDALDH1A1GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | claimed |