Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18832654 | 0.90 | LPAR1 (0.63) | LPAR1ACHESMPD1HDAC1HDAC8 | |
| SCHEMBL18832674 | 0.90 | LPAR1 (0.60) | LPAR1ACHESMPD1HDAC1HDAC8 | |
| SCHEMBL18832678 | 0.89 | LPAR1 (0.63) | LPAR1ACHESMPD1HDAC1HDAC8 | |
| SCHEMBL1561250 | 0.87 | LPAR1 (0.68) | LPAR1ACHESMPD1HDAC1HDAC8 | |
| SCHEMBL18832660 | 0.86 | LPAR1 (0.59) | LPAR1ACHESMPD1HDAC1HDAC8 | |
| SCHEMBL18832661 | 0.83 | LPAR1 (0.60) | LPAR1ALDH1A1LMNAMAPT | |
| SCHEMBL18832655 | 0.82 | LPAR1 (0.53) | LPAR1SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL18832675 | 0.80 | LPAR1 (0.61) | LPAR1NOX1NPC1RAB9AMEN1 | |
| SCHEMBL18832662 | 0.79 | LPAR1 (0.60) | LPAR1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL18832677 | 0.79 | LPAR1 (0.51) | LPAR1SMPD1HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | claimed |