Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1883304 | 1.00 | KMT2A (0.55) | KMT2ATACR1CYP2C19CYP1A2HSD17B10 | |
| SCHEMBL14385070 | 0.87 | KMT2A (0.43) | KMT2ATACR1CYP2C19CYP1A2HSD17B10 | |
| SCHEMBL4799364 | 0.84 | SRC (0.48) | KMT2ATACR1CYP2C19CYP1A2HSD17B10 | |
| SCHEMBL762079 | 0.84 | SRC (0.48) | KMT2ATACR1CYP2C19CYP1A2HSD17B10 | |
| SCHEMBL14278787 | 0.84 | SRC (0.48) | KMT2ATACR1CYP2C19CYP1A2HSD17B10 | |
| SCHEMBL22511875 | 0.82 | KMT2A (0.58) | KMT2ACYP1A2HSD17B10MEN1TSHR | |
| SCHEMBL9024661 | 0.81 | KMT2A (0.49) | KMT2ACYP2C19HSD17B10SMN1; SMN2TSHR | |
| SCHEMBL1883313 | 0.80 | CTSK (0.50) | KMT2A | |
| SCHEMBL11040399 | 0.79 | KMT2A (0.58) | KMT2ACYP2C19CYP1A2HSD17B10MEN1 | |
| SCHEMBL12880100 | 0.79 | KMT2A (0.58) | KMT2ACYP2C19CYP1A2HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935841-B2 | Bisphospholanes for use as catalysts in asymmetric reactions | DR. REDDY'S LABORATORIES LIMITED (IN) | 2011-05-03 | — | — | US | disclosed |
| US-20090099358-A1 | BISPHOSPHOLANES FOR USE AS CATALYSTS IN ASYMMETRIC REACTIONS | JACKSON PHILIP M | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099358-A1 | BISPHOSPHOLANES FOR USE AS CATALYSTS IN ASYMMETRIC REACTIONS | BPGM, PFKFB3, PFKFB4 | KMT2A 3857/4885TACR1 563/4885CYP2C19 1141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.