Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638535 | 0.86 | MAPT (0.59) | ALDH1A1HPGDMAPK1MAPTHSD17B10 | |
| SCHEMBL17609629 | 0.84 | HSD17B10 (0.47) | ALDH1A1HPGDMAPK1MAPTCYP2C9 | |
| SCHEMBL16122929 | 0.80 | MLKL (0.53) | ALDH1A1MAPK1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16058635 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPK1MAPTCYP2C9 | |
| SCHEMBL16363925 | 0.76 | MAPK1 (0.46) | ALDH1A1HPGDMAPK1MAPTMEN1 | |
| SCHEMBL17609493 | 0.75 | SMN1; SMN2 (0.55) | ALDH1A1HPGDMAPK1MEN1KMT2A | |
| SCHEMBL24476658 | 0.74 | MAPK1 (0.69) | ALDH1A1HPGDMAPK1MAPTHSD17B10 | |
| SCHEMBL9390364 | 0.73 | HPGD (0.51) | ALDH1A1HPGDMAPK1MAPTCYP2C9 | |
| SCHEMBL17609947 | 0.73 | TRPA1 (0.47) | MAPK1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL24476692 | 0.73 | KDM4E (0.66) | ALDH1A1HPGDMAPK1MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |