Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 6/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29832042 | 0.79 | TGFBR1 (0.56) | KDM4CALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL6108764 | 0.78 | KDM4C (0.45) | KDM4CRAB9ANPC1MEN1KMT2A | |
| SCHEMBL8197550 | 0.78 | SIGMAR1 (0.49) | KDM4CALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL5710973 | 0.75 | MEN1 (0.48) | KDM4CRAB9ANPC1MEN1KMT2A | |
| SCHEMBL4021549 | 0.74 | MEN1 (0.48) | KDM4CMEN1KMT2A | |
| SCHEMBL8195016 | 0.74 | MEN1 (0.46) | KDM4CALDH1A1MEN1KMT2A | |
| SCHEMBL14656744 | 0.73 | KDM4C (0.41) | KDM4CALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL23703927 | 0.71 | KDM4C (0.51) | KDM4CRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9673310 | 0.70 | KDM4C (0.53) | KDM4CRAB9ANPC1MEN1KMT2A | |
| SCHEMBL7460409 | 0.70 | MEN1 (0.46) | KDM4CRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |