Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29832042 | 0.81 | TGFBR1 (0.56) | KDM4CMEN1KMT2ATGFBR1LMNA | |
| SCHEMBL8197550 | 0.79 | SIGMAR1 (0.49) | KDM4CMEN1KMT2ATGFBR1P2RX3 | |
| SCHEMBL18834589 | 0.78 | SLC9A1 (0.48) | KDM4CMEN1KMT2ALMNANPC1 | |
| SCHEMBL6947360 | 0.76 | SMN1; SMN2 (0.45) | KDM4CMEN1KMT2ATP53LMNA | |
| SCHEMBL4021549 | 0.76 | MEN1 (0.48) | KDM4CMEN1KMT2A | |
| SCHEMBL8195016 | 0.75 | MEN1 (0.46) | KDM4CMEN1KMT2AP2RX3 | |
| SCHEMBL5710973 | 0.74 | MEN1 (0.48) | KDM4CMEN1KMT2ATGFBR1P2RX3 | |
| SCHEMBL4823935 | 0.71 | TGFBR1 (0.50) | KDM4CMEN1KMT2ATGFBR1P2RX3 | |
| SCHEMBL4813068 | 0.70 | TGFBR1 (0.55) | KDM4CMEN1KMT2ATGFBR1TP53 | |
| SCHEMBL7877948 | 0.70 | MTNR1A (0.50) | KDM4CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058295-A1 | Novel compounds as pharmaceutical agents | ELI LILLY AND COMPANY (US) | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058295-A1 | Novel compounds as pharmaceutical agents | TGFB1, TGFB2, TGFBR1 | KDM4C 4678/4885MEN1 404/4885KMT2A 4380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.