Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.41 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.41 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 15/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16122939 | 0.81 | GRIN1 (0.43) | P2RX3ADORA1 | |
| SCHEMBL16364030 | 0.79 | TRPC5 (0.47) | TRPC4TRPC5TRPC1P2RX3KCNH2 | |
| SCHEMBL20432257 | 0.77 | TRPC5 (0.50) | TRPC4TRPC5TRPC1P2RX3KCNH2 | |
| SCHEMBL18834534 | 0.77 | P2RX3 (0.42) | TRPC4TRPC5TRPC1P2RX3KCNH2 | |
| SCHEMBL19560542 | 0.77 | TRPC4 (0.44) | TRPC4TRPC5TRPC1TP53P2RX3 | |
| SCHEMBL19560513 | 0.74 | KCNH2 (0.38) | TRPC4TRPC5TRPC1P2RX3KCNH2 | |
| SCHEMBL21316296 | 0.74 | TRPC5 (0.45) | TRPC4TRPC5TRPC1TP53P2RX3 | |
| SCHEMBL16364000 | 0.74 | TRPC5 (0.48) | TRPC4TRPC5TRPC1P2RX3KCNH2 | |
| SCHEMBL16027833 | 0.73 | TRPC4 (0.66) | TRPC4TRPC5TRPC1TP53KCNH2 | |
| SCHEMBL16028471 | 0.73 | TRPC4 (0.59) | TRPC4TRPC5TRPC1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |