Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 14/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.40 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834234 | 0.81 | TRPC5 (0.43) | P2RX3MEN1ALDH1A1KMT2ATRPC4 | |
| SCHEMBL20432257 | 0.81 | TRPC5 (0.50) | P2RX3TSHRALDH1A1TRPC4TRPC5 | |
| SCHEMBL16364003 | 0.80 | TRPC4 (0.41) | P2RX3TRPC4TRPC5KCNH2TRPC1 | |
| SCHEMBL16364000 | 0.77 | TRPC5 (0.48) | P2RX3TRPC4TRPC5KCNH2TRPC1 | |
| SCHEMBL18834616 | 0.77 | TRPC4 (0.41) | P2RX3TRPC4TRPC5KCNH2TRPC1 | |
| SCHEMBL19375011 | 0.77 | P2RX3 (0.42) | P2RX3 | |
| SCHEMBL18834480 | 0.76 | TP53 (0.35) | TSHRMEN1ALDH1A1KMT2AHTT | |
| SCHEMBL19375602 | 0.75 | ADORA3 (0.43) | TSHRMEN1ALDH1A1KMT2ATRPC4 | |
| SCHEMBL18834196 | 0.74 | ALDH1A1 (0.40) | TSHRALDH1A1HTT | |
| SCHEMBL18834244 | 0.72 | TRPC4 (0.70) | TSHRMEN1ALDH1A1KMT2ATRPC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |