Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19375437 | 0.79 | TSHR (0.53) | TSHRSMN1; SMN2ENPP2GPBAR1CYSLTR1 | |
| SCHEMBL16902891 | 0.78 | TSHR (0.56) | TSHRSMN1; SMN2ENPP2GPBAR1CYSLTR1 | |
| SCHEMBL16845934 | 0.78 | TSHR (0.47) | TSHRSMN1; SMN2ENPP2GPBAR1CYSLTR1 | |
| SCHEMBL14724397 | 0.78 | TSHR (0.47) | TSHRSMN1; SMN2ENPP2GPBAR1CYSLTR1 | |
| SCHEMBL14412951 | 0.78 | KDM4E (0.47) | TSHRSMN1; SMN2 | |
| SCHEMBL29587500 | 0.78 | TAAR1 (0.60) | — | |
| SCHEMBL96382 | 0.78 | TAAR1 (0.60) | — | |
| SCHEMBL1776057 | 0.78 | MEP1B (0.54) | TSHRSMN1; SMN2ENPP2GPBAR1CYSLTR1 | |
| SCHEMBL92907 | 0.78 | CETP (0.55) | — | |
| SCHEMBL16902876 | 0.77 | TSHR (0.54) | TSHRSMN1; SMN2GPBAR1CYSLTR1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |