Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14724872 | 0.79 | TSHR (0.53) | TSHRSMN1; SMN2ENPP2GPBAR1CYSLTR1 | |
| SCHEMBL96382 | 0.78 | TAAR1 (0.60) | IDO1AGXTTAAR1 | |
| SCHEMBL18834801 | 0.78 | TSHR (0.47) | TSHRSMN1; SMN2ENPP2GPBAR1CYSLTR1 | |
| SCHEMBL29587500 | 0.78 | TAAR1 (0.60) | IDO1AGXTTAAR1 | |
| SCHEMBL16902891 | 0.78 | TSHR (0.56) | TSHRSMN1; SMN2ENPP2GPBAR1CYSLTR1 | |
| SCHEMBL16845934 | 0.78 | TSHR (0.47) | TSHRSMN1; SMN2ENPP2GPBAR1CYSLTR1 | |
| SCHEMBL358425 | 0.77 | LTA4H (0.67) | TSHRSMN1; SMN2TTRLTA4HCYP4F2 | |
| SCHEMBL16902876 | 0.77 | TSHR (0.54) | TSHRSMN1; SMN2GPBAR1CYSLTR1PRSS1 | |
| SCHEMBL551531 | 0.77 | TSHR (0.46) | TSHRSMN1; SMN2ENPP2GPBAR1CYSLTR1 | |
| SCHEMBL29661187 | 0.77 | LTA4H (0.67) | TSHRSMN1; SMN2TTRLTA4HCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562165-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2562163-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |