Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.43 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 15/20 | 0.42 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18835313 | 0.83 | TRPC4 (0.40) | TRPC4TRPC5KCNH2P2RX3TRPC1 | |
| SCHEMBL20432150 | 0.82 | TRPC4 (0.39) | TRPC4TRPC5KCNH2P2RX3TRPC1 | |
| SCHEMBL18834484 | 0.79 | TRPC5 (0.41) | TRPC4TRPC5KCNH2P2RX3TRPC1 | |
| SCHEMBL18835214 | 0.77 | P2RX3 (0.39) | TRPC5P2RX3 | |
| SCHEMBL20431970 | 0.77 | ALDH1A1 (0.43) | TRPC5P2RX3ALDH1A1POLB | |
| SCHEMBL18834916 | 0.77 | TRPC4 (0.45) | TRPC4TRPC5KCNH2P2RX3TRPC1 | |
| SCHEMBL19374820 | 0.76 | P2RX3 (0.42) | TRPC4TRPC5KCNH2P2RX3TRPC1 | |
| SCHEMBL19375125 | 0.76 | TRPC4 (0.45) | TRPC4TRPC5KCNH2P2RX3TRPC1 | |
| SCHEMBL19505412 | 0.76 | TRPC4 (0.41) | TRPC4TRPC5KCNH2P2RX3TRPC1 | |
| SCHEMBL19375127 | 0.75 | TRPC5 (0.59) | TRPC4TRPC5KCNH2P2RX3TRPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |