Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815415 | 0.80 | TAAR1 (0.48) | KDM4E | |
| SCHEMBL8845221 | 0.78 | TYR (0.40) | — | |
| SCHEMBL5587207 | 0.77 | MMP12 (0.35) | — | |
| SCHEMBL10642266 | 0.77 | TAAR1 (0.52) | KDM4E | |
| SCHEMBL6568148 | 0.74 | ALDH1A1 (0.39) | KDM4E | |
| SCHEMBL20483112 | 0.74 | ANPEP (0.36) | — | |
| SCHEMBL24072 | 0.73 | AOC3 (0.34) | — | |
| SCHEMBL6199970 | 0.72 | THRB (0.37) | — | |
| SCHEMBL28529484 | 0.71 | AOC3 (0.33) | — | |
| SCHEMBL16991374 | 0.69 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401281-A1 | PYRIMIDOPYRIMIDOINDAZOLE DERIVATIVE | MSD K.K. (JP) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010098367-A1 | PYRIMIDOPYRIMIDOINDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |