Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1883670 | 1.00 | GPR84 (0.43) | GPR84SLC22A6CNR2PPARGCNR1 | |
| SCHEMBL13156318 | 1.00 | GPR84 (0.43) | GPR84SLC22A6CNR2PPARGCNR1 | |
| SCHEMBL4751719 | 0.88 | GPR84 (0.51) | GPR84SLC22A6PPARGMAPTGPR132 | |
| SCHEMBL4751718 | 0.88 | GPR84 (0.51) | GPR84SLC22A6PPARGMAPTGPR132 | |
| SCHEMBL4748587 | 0.86 | SLC22A6 (0.48) | GPR84SLC22A6MAPTGABRR1LMNA | |
| SCHEMBL5486996 | 0.86 | SLC22A6 (0.48) | GPR84SLC22A6MAPTGABRR1LMNA | |
| SCHEMBL668060 | 0.86 | SLC22A6 (0.48) | GPR84SLC22A6MAPTGABRR1LMNA | |
| SCHEMBL667255 | 0.86 | SLC22A6 (0.48) | GPR84SLC22A6MAPTGABRR1LMNA | |
| SCHEMBL4747079 | 0.86 | SLC22A6 (0.48) | GPR84SLC22A6MAPTGABRR1LMNA | |
| SCHEMBL4749042 | 0.86 | GPR84 (0.54) | GPR84PPARGMAPTGPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217192-B2 | Production method of (2E,6Z,8E)-N-isobutyl-2,6,8-decatrienamide (spilanthol), and food or drink, fragrance or cosmetic, or pharmaceutical comprising the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20110105773-A1 | PRODUCTION METHOD OF (2E,6Z,8E)-N-ISOBUTYL-2,6,8-DECATRIENAMIDE (SPILANTHOL), AND FOOD OR DRINK, FRAGRANCE OR COSMETIC, OR PHARMACEUTICAL COMPRISING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-05 | — | — | US | disclosed |
| EP-2236489-A1 | METHOD FOR PRODUCTION OF (2E,6Z,8E)-N-ISOBUTYL-2,6,8-DECATRIENAMIDE (SPILANTHOL), AND FOODS, BEVERAGES, COSMETICS AND PHARMACEUTICAL PREPARATIONS EACH COMPRISING THE COMPOUND | Takasago International Corporation (JP) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105773-A1 | PRODUCTION METHOD OF (2E,6Z,8E)-N-ISOBUTYL-2,6,8-DECATRIENAMIDE (SPILANTHOL), AND FOOD OR DRINK, FRAGRANCE OR COSMETIC, OR PHARMACEUTICAL COMPRISING THE SAME | NISCH, FAAH2, ADH5 | GPR84 1129/4885SLC22A6 2962/4885CNR2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.