Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | PAM | P19021 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17212331 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL7941998 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11908231 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL3693883 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11909432 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11908905 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL5730879 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL15963994 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL9706868 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL11433305 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10125337-B2 | Branched diesters and methods of making and using the same | TRENT UNIVERSITY (CA) | 2018-11-13 | — | — | US | disclosed |
| US-20170137739-A1 | BRANCHED DIESTERS AND METHODS OF MAKING AND USING THE SAME | TRENT UNIVERSITY (CA) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10125337-B2 | Branched diesters and methods of making and using the same | DGKG, SQLE, DGAT2 | DGKA 4/4885PRSS1 4274/4885PRSS2 3592/4885 |
| US-20170137739-A1 | BRANCHED DIESTERS AND METHODS OF MAKING AND USING THE SAME | ELOVL3, SCD, PTGER3 | DGKA 19/4885PRSS1 3833/4885PRSS2 3575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.