Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236991 | 0.77 | GPR84 (0.49) | GPR84TP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6999959 | 0.76 | KDM4C (0.48) | GPR84KDM4CTP53MEN1KMT2A | |
| SCHEMBL8974784 | 0.76 | GPR84 (0.50) | GPR84KDM4CTP53MEN1KMT2A | |
| SCHEMBL3261738 | 0.69 | GPR84 (1.00) | GPR84 | |
| SCHEMBL11379657 | 0.69 | GPR84 (0.45) | GPR84KDM4CTP53MEN1KMT2A | |
| SCHEMBL11376319 | 0.69 | GPR84 (0.75) | GPR84 | |
| SCHEMBL8709983 | 0.69 | GPR84 (0.77) | GPR84 | |
| SCHEMBL30361812 | 0.68 | GPR84 (1.00) | GPR84 | |
| SCHEMBL17375502 | 0.68 | GPR84 (1.00) | GPR84 | |
| SCHEMBL5309531 | 0.67 | TP53 (0.63) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604260-B1 | NOVEL HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | SHIONOGI & CO (JP) | 2017-05-10 | — | — | EP | disclosed |