Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242561 | 0.76 | GPR84 (0.52) | KDM4CGPR84TP53MEN1KMT2A | |
| SCHEMBL18836780 | 0.76 | GPR84 (0.52) | KDM4CGPR84TP53MEN1KMT2A | |
| SCHEMBL8974784 | 0.76 | GPR84 (0.50) | KDM4CGPR84TP53MEN1KMT2A | |
| SCHEMBL3236991 | 0.73 | GPR84 (0.49) | GPR84TP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11376319 | 0.69 | GPR84 (0.75) | GPR84 | |
| SCHEMBL8709983 | 0.69 | GPR84 (0.77) | GPR84 | |
| SCHEMBL11379657 | 0.69 | GPR84 (0.45) | KDM4CGPR84TP53MEN1KMT2A | |
| SCHEMBL8154153 | 0.67 | GPR84 (0.53) | KDM4CGPR84 | |
| SCHEMBL317622 | 0.67 | — | — | |
| SCHEMBL5298937 | 0.66 | TP53 (0.71) | TP53MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077372-A1 | NEW DERIVATIVES OF PYRAZOLO(3,4-d)PYRIMIDINE, PREPARATION METHOD THEREOF AND REMEDY CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-04-27 | — | — | EP | claimed |
| WO-1982003626-A1 | NEW DERIVATIVES OF PYRAZOLO(3,4-D)PYRIMIDINE,PREPARATION METHOD THEREOF AND REMEDY CONTAINING THEM | GAURI KAILASH KUMAR | 1982-10-28 | — | — | WO | claimed |
| EP-0063381-A1 | Pyrazolo(3-4-d) pyrimidines, process for their preparation and pharmaceutical compositions containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-10-27 | — | — | EP | claimed |
| WO-2024209647-A1 | PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING PATTERNED CURED PRODUCT, CURED PRODUCT, AND ELECTRONIC COMPONENT | ＨＤマイクロシステムズ株式会社 | 2024-10-10 | — | — | WO | disclosed |
| EP-1033369-B1 | 5H-PYRANO [2,3-d:6,5-d']DIPYRIMIDINE DERIVATIVES HAVING AN ANTIBACTERIAL, ANTIVIRAL AND IMMUNO-MODULATING ACTIVITY | NATURAL DRUG SCIENCES L L C (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6340755-B1 | IMMUNOMMODULATORS, BACTERICIDES AND VIRICIDES | NATURAL DRUG SCIENCES LLC | 2002-01-22 | — | — | US | disclosed |
| US-6133273-A | DISORDERS ASSOCIATED WITH BONE LOSS BY INCREASED TRANSCRIPTION AND ELEVATION OF PLASMA CALCITONIN LEVELS INCLUDING PAGET'S DISEASE, POST MENOPAUSAL OSTEOPOROSIS, SENILE OSTEOPOROSIS, AND GLUCOCORTICOID-INDUCED OSTEOPOROSIS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1033369-A1 | 5H-PYRANO [2,3-d:6,5-d']DIPYRIMIDINE DERIVATIVES HAVING AN ANTIBACTERIAL, ANTIVIRAL AND IMMUNO-MODULATING ACTIVITY | Tets, Viktor Veniaminovich (RU) | 2000-09-06 | — | — | EP | disclosed |
| US-5069708-A | PRE-AND POSTEMERGENCE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| US-4511557-A | CALF'S BLOOD DIAYSATE AS VASODILATION POTENTIATOR | GAURI KAILASH KUMAR (DE) | 1985-04-16 | — | — | US | disclosed |
| EP-0106309-A2 | Biologically active extracts, process for their manufacture, medicinal and cosmetical preparations comprising them, and their use as additives in foodstuffs and stimulants | Gauri, Kailash Kumar, Dr. Prof. (DE) | 1984-04-25 | — | — | EP | disclosed |
| EP-0077372-A1 | NEW DERIVATIVES OF PYRAZOLO(3,4-d)PYRIMIDINE, PREPARATION METHOD THEREOF AND REMEDY CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-04-27 | — | — | EP | disclosed |
| WO-1982003626-A1 | NEW DERIVATIVES OF PYRAZOLO(3,4-D)PYRIMIDINE,PREPARATION METHOD THEREOF AND REMEDY CONTAINING THEM | GAURI KAILASH KUMAR | 1982-10-28 | — | — | WO | disclosed |
| EP-0063381-A1 | Pyrazolo(3-4-d) pyrimidines, process for their preparation and pharmaceutical compositions containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-10-27 | — | — | EP | disclosed |