SCHEMBL18837357

SCHEMBL18837357

CC(C)CCCC(C)CCOc1ccc2ccccc2c1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 3/20 0.55
▸ RAB9A P51151 3/20 0.55
▸ TDP1 Q9NUW8 3/20 0.51
▸ KDM4E B2RXH2 3/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ GSTO1 P78417 1/20 0.47
▸ HRH3 Q9Y5N1 3/20 0.47
▸ DRD3 P35462 1/20 0.47
▸ PPARG P37231 1/20 0.46
▸ MAPT P10636 2/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ LMNA P02545 1/20 0.45
▸ AGXT P21549 2/20 0.45
▸ HTT P42858 1/20 0.44
▸ ALOX5 P09917 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.43
▸ TLR8 Q9NR97 1/20 0.43
▸ HDAC1 Q13547 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16473543 0.89 NPC1 (0.67) NPC1RAB9ATDP1KDM4EMAPK1
SCHEMBL7619788 0.87 KDM4E (0.61) NPC1RAB9ATDP1KDM4EMAPK1
SCHEMBL7585689 0.85 GSTO1 (0.45) NPC1RAB9ATDP1MAPK1GSTO1
SCHEMBL6857008 0.84 TDP1 (0.58) TDP1MAPK1GSTO1MAPTSMN1; SMN2
SCHEMBL16340342 0.84 TDP1 (0.58) TDP1MAPK1GSTO1MAPTSMN1; SMN2
SCHEMBL4762110 0.82 KCNA3 (0.52) TDP1MAPK1LMNAALOX5HDAC1
SCHEMBL7536898 0.82 KCNA3 (0.52) TDP1MAPK1LMNAALOX5HDAC1
SCHEMBL7271691 0.82 GSTO1 (0.46) NPC1RAB9ATDP1MAPK1GSTO1
SCHEMBL7271683 0.82 GSTO1 (0.46) NPC1RAB9ATDP1MAPK1GSTO1
SCHEMBL7278712 0.81 RARB (0.60) KDM4EMAPK1GSTO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3374476-A1 LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME ExxonMobil Research and Engineering Company (US) 2018-09-19 — — EP claimed
WO-2017083065-A1 LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME EXXONMOBIL RESEARCH AND ENGINERRING COMPANY (US) 2017-05-18 — — WO claimed
US-20170137734-A1 LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2017-05-18 — — US claimed
EP-3374476-A1 LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME ExxonMobil Research and Engineering Company (US) 2018-09-19 — — EP disclosed
US-9822323-B2 Low viscosity low volatility lubricating oil base stocks and processes for preparing same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-11-21 — — US disclosed
US-9822323-B2 Low viscosity low volatility lubricating oil base stocks and processes for preparing same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-11-21 — — US disclosed
US-9822323-B2 Low viscosity low volatility lubricating oil base stocks and processes for preparing same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-11-21 — — US disclosed
US-20170137734-A1 LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2017-05-18 — — US disclosed
US-20170137734-A1 LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2017-05-18 — — US disclosed
US-20170137734-A1 LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2017-05-18 — — US disclosed
WO-2017083065-A1 LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME EXXONMOBIL RESEARCH AND ENGINERRING COMPANY (US) 2017-05-18 — — WO disclosed
WO-2017083065-A1 LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME EXXONMOBIL RESEARCH AND ENGINERRING COMPANY (US) 2017-05-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170137734-A1 LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME DEGS1, RPS20, KCNK10 NPC1 1765/4885RAB9A 3064/4885TDP1 1390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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